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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Arrb2
arrestin, beta 2
MGI:99474
16 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Arrb2tm1.1(KOMP)Vlcg/Arrb2+
B6N(Cg)-Arrb2tm1.1(KOMP)Vlcg/J
increased circulating free fatty acids level J:211773
Arrb2tm1.1(KOMP)Vlcg/Arrb2tm1.1(KOMP)Vlcg
B6N(Cg)-Arrb2tm1.1(KOMP)Vlcg/J
increased circulating alkaline phosphatase level J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
increased circulating phosphate level J:211773
increased grip strength J:211773
Arrb2tm1Rjl/Arrb2tm1Rjl
involves: 129X1/SvJ * C57BL/6
abnormal body temperature homeostasis J:59162
abnormal circulating tumor necrosis factor level J:112607
abnormal lymphocyte physiology J:76872
increased acute inflammation J:112607
increased chemically-elicited antinociception J:59162
increased circulating interleukin-6 level J:112607
increased interleukin-6 secretion J:112607
increased interleukin-12b secretion J:112607
increased susceptibility to endotoxin shock J:112607
increased tumor necrosis factor secretion J:112607

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory