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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dsg3
desmoglein 3
MGI:99499
58 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dsg3bal-Pas/Dsg3bal-Pas
129S2.Cg-Dsg3bal-Pas 		abnormal hair follicle morphology J:42792
abnormal hair shaft morphology J:42792
alopecia J:42792
blistering J:42792
oral mucosa blisters J:42792
premature hair loss J:42792
sparse hair J:42792
thin epidermis stratum granulosum J:42792
Dsg3bal/Dsg3bal
C57BL/6J-Dsg3bal/J 		abnormal hair follicle morphology J:42792
abnormal hair growth J:13702
alopecia J:13702
blistering J:42792
cutaneous mastocytosis J:18223
decreased body size J:13702
increased IgE level J:18223
sparse hair J:13702
Dsg3sqk/Dsg3sqk
C57BL/6-Dsg3sqk 		abnormal epidermis stratum spinosum morphology J:219200
abnormal epiglottis morphology J:219200
abnormal hair growth J:219200
abnormal keratinocyte physiology J:219200
abnormal laryngeal cartilage morphology J:219200
abnormal larynx morphology J:219200
abnormal respiratory system morphology J:219200
abnormal snout skin morphology J:219200
abnormal subglottis morphology J:219200
abnormal thoracic cage shape J:219200
abnormal tongue morphology J:219200
abnormal tracheal ciliated epithelium morphology J:219200
absent suprabasal layer J:219200
alopecia J:219200
cachexia J:219200
conjunctivitis J:219200
decreased B cell number J:219200
decreased body size J:219200
decreased circulating leptin level J:219200
decreased double-positive T cell number J:219200
decreased immature B cell number J:219200
decreased lymphocyte cell number J:219200
decreased pre-B cell number J:219200
decreased single-positive T cell number J:219200
decreased subcutaneous adipose tissue amount J:219200
decreased total body fat amount J:219200
decreased transitional stage B cell number J:219200
epiglottis hyperplasia J:219200
female infertility J:219200
focal hair loss J:219200
increased neutrophil cell number J:219200
increased susceptibility to infection J:219200
larynx stenosis J:219200
meteorism J:219200
mouth mucosal ulcer J:219200
postnatal growth retardation J:219200
postnatal lethality, incomplete penetrance J:219200
respiratory distress J:219200
sparse hair J:219200
stridor J:219200
subglottis stenosis J:219200
thick epidermis J:219200
thick epidermis stratum spinosum J:219200
Dsg3tm1Stan/Dsg3tm1Stan
involves: 129X1/SvJ * C57BL/6J 		abnormal cell adhesion J:40804
abnormal hair cycle J:40804
abnormal hair shaft morphology J:40804
acantholysis J:40804
alopecia J:40804
blistering J:40804
conjunctivitis J:40804
decreased body size J:40804
decreased body weight J:40804
decreased total body fat amount J:40804
lethality at weaning, incomplete penetrance J:40804
mouth mucosal ulcer J:40804
postnatal growth retardation J:40804
skin lesions J:40804
weight loss J:40804
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory