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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hspa1b
heat shock protein 1B
MGI:99517
11 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hspa1btm1.1Msk/Hspa1btm1.1Msk
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal cell physiology J:72943
Hspa1btm1Bwy/Hspa1btm1Bwy
B6.129P2-Hspa1btm1Bwy 		increased cerebral infarct size J:103999
increased susceptibility to ischemic brain injury J:103999
Hspa1btm1Clib/Hspa1btm1Clib
involves: 129P2/OlaHsd * C57BL/6 		abnormal response/metabolism to endogenous compounds J:123913
decreased body temperature J:123913
increased susceptibility to induced morbidity/mortality J:123913
Hspa1btm1Clib/Hspa1btm1Clib
involves: 129P2/OlaHsd * C57BL/6J 		abnormal nitric oxide homeostasis J:76801
abnormal response/metabolism to endogenous compounds J:76801
decreased body temperature J:76801
increased interleukin-6 secretion J:76801
increased susceptibility to induced morbidity/mortality J:76801
Hspa1btm1Jss/Hspa1btm1Jss
involves: C57BL/6 		increased cellular sensitivity to oxidative stress J:97232
increased kidney apoptosis J:97232
Hspa1btm1Msk/Hspa1b+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal cell physiology J:72943
Hspa1btm1Msk/Hspa1btm1Msk
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal cell physiology J:72943
increased sensitivity to induced cell death J:72943
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory