Pde4d Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pde4d
phosphodiesterase 4D, cAMP specific
MGI:99555

12 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pde4d^tm1Mct/Pde4d^tm1Mct B6.129P2-Pde4d^tm1Mct/Mmucd	abnormal behavioral response to anesthetic	J:304450
Pde4d^tm1Mct/Pde4d^tm1Mct involves: 129P2/OlaHsd	increased cardiac muscle contractility	J:96125
Pde4d^tm1Mct/Pde4d^tm1Mct involves: 129P2/OlaHsd * 129X1/SvJ	postnatal lethality, incomplete penetrance	J:58116
Pde4d^tm1Mct/Pde4d^tm1Mct involves: 129P2/OlaHsd * C57BL/6	abnormal tumor necrosis factor level	J:94853
	decreased body weight	J:58116
	decreased litter size	J:58116
	decreased superovulation rate	J:58116
	normal immune system phenotype	J:106828
	impaired neutrophil chemotaxis	J:94853
	impaired neutrophil recruitment	J:94853
	postnatal growth retardation	J:58116
	postnatal lethality, incomplete penetrance	J:58116
	reduced female fertility	J:58116
Pde4d^tm2Mct/Pde4d^tm2Mct involves: 129P2/OlaHsd * C57BL/6	postnatal lethality, incomplete penetrance	J:58116

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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