S1pr2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

S1pr2
sphingosine-1-phosphate receptor 2
MGI:99569

30 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
S1pr1^tm1Rlp/S1pr1^tm1Rlp S1pr2^tm1Rlp/S1pr2^tm1Rlp involves: 129S6/SvEvTac * C57BL/6	abnormal angiogenesis	J:106055
	embryonic lethality during organogenesis, complete penetrance	J:106055
	hemorrhage	J:106055
S1pr1^tm1Rlp/S1pr1^tm1Rlp S1pr3^tm1Rlp/S1pr3^tm1Rlp S1pr2^tm1Rlp/S1pr2^tm1Rlp involves: 129S6/SvEvTac * C57BL/6	abnormal angiogenesis	J:106055
	embryonic lethality during organogenesis, complete penetrance	J:106055
	hemorrhage	J:106055
S1pr2^tm1Jch/S1pr2^tm1Jch S1pr3^tm1Jch/S1pr3^tm1Jch involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	abnormal inner ear vestibule morphology	J:118369
	abnormal maternal nurturing	J:77809
	abnormal posture	J:118369
	abnormal vestibular system physiology	J:118369
	absent startle reflex	J:118369
	absent vestibular hair cell stereocilia	J:118369
	cochlear ganglion degeneration	J:118369
	cochlear inner hair cell degeneration	J:118369
	cochlear outer hair cell degeneration	J:118369
	decreased litter size	J:77809
	decreased vertical activity	J:118369
	degeneration of organ of Corti supporting cells	J:118369
	head tilt	J:118369
	impaired righting response	J:118369
	impaired swimming	J:118369
	limb grasping	J:118369
	organ of Corti degeneration	J:118369
	perinatal lethality, incomplete penetrance	J:77809
	utricular macular degeneration	J:118369
	vestibular hair cell degeneration	J:118369
	vestibular saccular macula degeneration	J:118369
S1pr3^tm1Jch/S1pr3⁺ S1pr2^tm1Jch/S1pr2^tm1Jch involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	absent startle reflex	J:118369
S1pr3^tm1Rlp/S1pr3^tm1Rlp S1pr2^tm1Rlp/S1pr2^tm1Rlp involves: 129S6/SvEvTac * C57BL/6	abnormal vascular endothelial cell morphology	J:106055
	cochlear ganglion degeneration	J:121165
	head tilt	J:121165
	hemorrhage	J:106055
	increased miscarriage rate	J:106055
	lethality throughout fetal growth and development, incomplete penetrance	J:106055
	prenatal lethality, incomplete penetrance	J:121165
	reduced fertility	J:106055
	skin edema	J:106055

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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