Drd1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Drd1
dopamine receptor D1
MGI:99578

73 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Drd1^tm1(cre)Rpa/Drd1⁺ Gad1^tm1Rpa/Gad1^tm1.1Rpa involves: 129S4/SvJaeSor * C57BL/6	abnormal motor coordination/balance	J:138586
	normal behavior/neurological phenotype	J:138586
	decreased grip strength	J:138586
	limb grasping	J:138586
Drd1^{tm1.1(IL2RA/Venus)Koba}/Drd1⁺ B6.129S6-Drd1^{tm1.1(IL2RA/Venus)Koba}	abnormal neuron morphology	J:184374
	abnormal operant conditioning behavior	J:184374
	normal behavior/neurological phenotype	J:184374
Drd1^tm1Jcd/Drd1⁺ Drd2^tm1Ebo/Drd2^tm1Ebo involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	normal mortality/aging	J:91781
Drd1^tm1Jcd/Drd1^tm1Jcd Drd2^tm1Ebo/Drd2⁺ involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal duodenum morphology	J:91781
	abnormal eating behavior	J:91781
	abnormal stomach morphology	J:91781
	gastrointestinal hemorrhage	J:91781
	intestinal ulcer	J:91781
	postnatal growth retardation	J:91781
	premature death	J:91781
	small intestinal inflammation	J:91781
Drd1^tm1Jcd/Drd1^tm1Jcd Drd2^tm1Ebo/Drd2^tm1Ebo involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal digestive system development	J:91781
	abnormal digestive system physiology	J:91781
	abnormal hypothalamus physiology	J:91781
	abnormal intestinal smooth muscle morphology	J:91781
	abnormal intestine morphology	J:91781
	absent gastric milk in neonates	J:91781
	aphagia	J:91781
	decreased body size	J:91781
	decreased locomotor activity	J:91781
	gastrointestinal hemorrhage	J:91781
	normal nervous system phenotype	J:91781
	postnatal growth retardation	J:91781
	postnatal lethality, complete penetrance	J:91781
Drd1^tm1Jcd/Drd1^tm1Jcd Drd3^tm1Dac/Drd3^tm1Dac involves: 129S4/SvJae * C57BL/6	abnormal spatial learning	J:102600
	normal behavior/neurological phenotype	J:102600
	behavioral despair	J:102600
	decreased body size	J:102600
	decreased locomotor activity	J:102600
	decreased vertical activity	J:102600
	impaired coordination	J:102600
	impaired swimming	J:102600
	increased thigmotaxis	J:102600
Drd1^tm2.1Stl/Drd1^tm2.1Stl Drd5^tm1.1Stl/Drd5^tm1.1Stl Tg(Camk2a-cre)T29-1Stl/0 involves: BALB/c * C57BL * C57BL/6	abnormal long-term potentiation	J:211355
	decreased fear-related response	J:211355
	impaired contextual conditioning behavior	J:211355
Drd1^tm2Jcd/Drd1⁺ either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * CD-1)	no abnormal phenotype detected	J:120582
Drd1^tm2Jcd/Drd1⁺ Tg(EIIa-cre)C5379Lmgd/0 involves: 129S4/SvJae * BALB/c * CD-1 * FVB/N	abnormal forebrain morphology	J:120582
	abnormal hippocampus morphology	J:120582
	abnormal nervous system physiology	J:120582
	abnormal posture	J:120582
	abnormal striatum morphology	J:120582
	bradykinesia	J:120582
	decreased brain size	J:120582
	decreased brain weight	J:120582
	decreased forebrain size	J:120582
	decreased forebrain volume	J:120582
	decreased pulmonary respiratory rate	J:120582
	dystonia	J:120582
	gliosis	J:120582
	impaired balance	J:120582
	impaired righting response	J:120582
	myoclonus	J:120582
	postnatal lethality, complete penetrance	J:120582
Drd1^tm2Jcd/Drd1⁺ Tg(Camk2a-cre)2Gsc/0 involves: 129S4/SvJae * FVB/N	abnormal brain wave pattern	J:120070
	abnormal cerebral cortex morphology	J:120070
	abnormal dentate gyrus morphology	J:120070
	abnormal forebrain morphology	J:120070
	abnormal microglial cell physiology	J:120070
	abnormal nervous system morphology	J:120070
	abnormal nervous system physiology	J:120070
	astrocytosis	J:120070
	decreased body weight	J:120070
	decreased brain size	J:120070
	decreased brain weight	J:120070
	decreased hippocampus volume	J:120070
	decreased striatum size	J:120070
	dystonia	J:120070
	enlarged lateral ventricles	J:120070
	increased locomotor activity	J:120070
	increased vertical activity	J:120070
	limb grasping	J:120070
	seizures	J:120070
	striatum atrophy	J:120070
	trunk curl	J:120070
Or8a1^{tm41(Drd1)Mom}/Or8a1^{tm41(Drd1)Mom} B6;129P2-Or8a1^{tm41(Drd1)Mom}/MomJ	abnormal olfactory sensory neuron morphology	J:260975
	decreased olfactory sensory neuron number	J:260975
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Drd1^tm1(cre)Rpa/Drd1⁺ involves: C57BL/6	normal adipose tissue phenotype	J:196157
	normal growth/size/body region phenotype	J:196157
	normal homeostasis/metabolism phenotype	J:196157
	hyperactivity	J:196157

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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