Ryr2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ryr2
ryanodine receptor 2, cardiac
MGI:99685

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs}/Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs} Trp53^tm1Sia/Trp53⁺ involves: 129X1/SvJ * C57BL/6 * CBA	increased rhabdomyosarcoma incidence	J:117828
	increased tumor incidence	J:117828
Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs}/Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs} Trp53^tm1Sia/Trp53^tm1Sia involves: 129X1/SvJ * C57BL/6 * CBA	increased rhabdomyosarcoma incidence	J:117828
	increased tumor incidence	J:117828
	myositis	J:117828
Ryr2^tm2.1Wex/Ryr2^tm2.1Wex Tg(Myh6-EGFP/AC3I)#Mean/0 B6.Cg-Ryr2^tm2.1Wex Tg(Myh6-EGFP/AC3I)#Mean	ventricular tachycardia	J:179475

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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