Cttn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cttn
cortactin
MGI:99695

21 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cttn^{Gt(RRS284)Byg}/Cttn⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal cell morphology	J:158029
Cttn^{Gt(RRS284)Byg}/Cttn⁺ involves: 129P2/OlaHsd * C57BL/6	transmission ratio distortion	J:158029
Cttn^{Gt(RRS284)Byg}/Cttn^{Gt(RRS284)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal preimplantation embryo development	J:158029
	abnormal secondary polar body morphology	J:158029
	embryonic lethality before implantation, complete penetrance	J:158029
	failure of zygotic cell division	J:158029
Cttn^tm1.1Okab/Cttn^tm1.1Okab involves: 129S4/SvJae * C57BL/6 * SJL	normal cellular phenotype	J:155986
Cttn^tm1.2Dvst/Cttn⁺ B6.Cg-Cttn^tm1.2Dvst	preweaning lethality, incomplete penetrance	J:177602
Cttn^tm1.2Dvst/Cttn^tm1.2Dvst B6.Cg-Cttn^tm1.2Dvst	preweaning lethality, incomplete penetrance	J:177602
Cttn^tm1.2Dvst/Cttn^tm1.2Dvst B6.Cg-Cttn^tm1.2Dvst	normal reproductive system phenotype	J:177602
Cttn^tm1.2Dvst/Cttn^tm1.2Dvst either: B6.Cg-Cttn^tm1.2Dvst or (involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2 * SJL)	abnormal blood vessel morphology	J:177602
	abnormal cellular extravasation	J:177602
	abnormal leukocyte adhesion	J:177602
	abnormal leukocyte migration	J:177602
	abnormal lung endothelial cell physiology	J:177602
	abnormal neutrophil physiology	J:177602
	abnormal vascular endothelial cell physiology	J:177602
	increased vascular permeability	J:177602
Cttn^tm1.2Dvst/Cttn^tm1.2Dvst involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL	abnormal sex determination	J:177602
	normal mortality/aging	J:177602
Cttn^tm1.2Okab/Cttn^tm1.2Okab involves: 129S4/SvJae * BALB/cJ * C57BL/6 * SJL	normal cellular phenotype	J:155986
Cttn^{tm1b(EUCOMM)Hmgu}/Cttn^{tm1b(EUCOMM)Hmgu} C57BL/6N-Cttn^{tm1b(EUCOMM)Hmgu}/H	decreased thigmotaxis	J:211773
	tremors	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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