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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bax
BCL2-associated X protein
MGI:99702
40 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Baxtm1Dlo/Baxtm1Dlo
involves: 129P2/OlaHsd 		decreased apoptosis J:66953
decreased neuron apoptosis J:39573, J:66953
Baxtm1Ofxa/Baxtm1Ofxa
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased neuron apoptosis J:61471
Baxtm1Sjk/Bax+
involves: 129X1/SvJ 		abnormal sympathetic neuron morphology J:35372
increased motor neuron number J:35372
Baxtm1Sjk/Baxtm1Sjk
B6.129X1-Baxtm1Sjk/J 		abnormal seminiferous tubule morphology J:103605
abnormal spermatogenesis J:103605
arrest of male meiosis J:103605
azoospermia J:103605
decreased body weight J:103605
decreased testis weight J:103605
male infertility J:103605
normal nervous system phenotype J:122607
Baxtm1Sjk/Baxtm1Sjk
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 		abnormal axon extension J:100886
abnormal dorsal root ganglion morphology J:100886
increased sensory neuron number J:100886
Baxtm1Sjk/Baxtm1Sjk
involves: 129X1/SvJ 		abnormal facial motor nucleus morphology J:35372
abnormal phrenic nerve morphology J:91066
abnormal proprioceptive neuron morphology J:197913
abnormal seminiferous tubule morphology J:29253
abnormal superior cervical ganglion morphology J:35372
abnormal sympathetic neuron morphology J:35372
arrest of spermatogenesis J:29253
azoospermia J:29253
decreased neuron apoptosis J:35372
enlarged spleen J:29253
increased atretic ovarian follicle number J:29253
increased B cell number J:29253
increased male germ cell apoptosis J:29253
increased motor neuron number J:35372
increased sensory neuron number J:197913
increased thymocyte number J:29253
male infertility J:29253
normal nervous system phenotype J:192549
Baxtm1Sjk/Baxtm1Sjk
involves: 129X1/SvJ * C57BL/6 		abnormal dorsal root ganglion morphology J:83461
abnormal ovarian folliculogenesis J:52574
increased mature ovarian follicle number J:52574
uterus hypertrophy J:52574
Tg(Igk-V21-Bax)1967Bvn/0
involves: FVB/N 		abnormal kidney morphology J:89049
abnormal plasma cell morphology J:89049
increased IgA level J:89049
increased IgE level J:89049
increased IgG1 level J:89049
increased IgG2a level J:89049
increased IgG level J:89049, J:90901
increased IgM level J:89049
increased immunoglobulin level J:89049
increased transitional stage B cell number J:89049
increased urine protein level J:89049
renal cast J:89049
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory