Gpd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
MGI:99778

25 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gpd2^tm1Lbr/Gpd2⁺ involves: 129X1/SvJ * C57BL/6J	decreased body weight	J:78828
Gpd2^tm1Lbr/Gpd2^tm1Lbr B6.129X1-Gpd2^tm1Lbr	decreased body mass index	J:78828
	decreased epididymal fat pad weight	J:78828
	decreased litter size	J:78828
	decreased parametrial fat pad weight	J:78828
	decreased susceptibility to weight gain	J:78828
	decreased white adipose tissue amount	J:78828
	normal homeostasis/metabolism phenotype	J:78828
	postnatal lethality, incomplete penetrance	J:78828
	prenatal lethality, incomplete penetrance	J:78828
	reduced fertility	J:78828
Gpd2^tm1Lbr/Gpd2^tm1Lbr involves: 129X1/SvJ * C57BL/6J	decreased body weight	J:78828
Gpd2^tm1Lbr/Gpd2^tm1Lbr involves: 129X1/SvJ * C57BL/6J	normal mortality/aging	J:78828
Gpd2^tm1Tka/Gpd2^tm1Tka B6.Cg-Gpd2^tm1Tka	abnormal eating behavior	J:87244
	abnormal triiodothyronine level	J:87244
	decreased body size	J:87244
	decreased body weight	J:87244
	decreased brown adipose tissue mass	J:87244
	decreased brown fat cell lipid droplet size	J:87244
	decreased circulating insulin level	J:124766
	decreased oxygen consumption	J:87244
	impaired adaptive thermogenesis	J:87244
	increased body temperature	J:87244
	increased circulating cholesterol level	J:124766
	increased circulating thyroxine level	J:87244
	increased circulating triiodothyronine level	J:87244
Gpd2^tm1Tka/Gpd2^tm1Tka involves: C57BL/6 * CBA	decreased body weight	J:75839
Gpd2^tm1Tka/Gpd2^tm1Tka involves: C57BL/6 * CBA	decreased insulin secretion	J:75839

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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