Chrna7 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
MGI:99779

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Agrn^tm4Jrs/Agrn^tm4Jrs Chrna1^tm1Klee/Chrna1^tm1Klee Chrna7^tm1Bay/Chrna7^tm1Bay involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6	failure of neuromuscular synapse presynaptic differentiation	J:161300
Chrna3^tm1.1Hwrt/Chrna3^tm1.1Hwrt Chrna7^tm1Bay/Chrna7^tm1Bay involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6	abnormal excitatory postsynaptic potential	J:157611
Chrna7^tm1Bay/Chrna7^tm1Bay Chrnb2^tm1Mdb/Chrnb2^tm1Mdb involves: 129S7/SvEvBrd * C57BL/6J	normal behavior/neurological phenotype	J:94667
	decreased anxiety-related response	J:94667
	enhanced coordination	J:94667
	hyperactivity	J:94667
	impaired passive avoidance behavior	J:94667
Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ Chrna7^{tm2.1(cre)Swr}/Chrna7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal abdominal wall morphology	J:223063
	abnormal craniofacial morphology	J:223063
	abnormal dorsal root ganglion morphology	J:223063
	abnormal limb bone morphology	J:223063
	abnormal retina pigment epithelium morphology	J:223063
	abnormal rostral-caudal axis patterning	J:223063
	abnormal tail morphology	J:223063
	anemia	J:223063
	delayed caudal neuropore closure	J:223063
	dorsal root ganglion hypoplasia	J:223063
	normal embryo phenotype	J:223063
	enlarged liver	J:223063
	enlarged pancreas	J:223063
	enlarged salivary gland	J:223063
	flat head	J:223063
	hunched posture	J:223063
	macrodontia	J:223063
	omphalocele	J:223063
	perinatal lethality, complete penetrance	J:223063
	short mandible	J:223063
	spina bifida	J:223063

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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