Lhx1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lhx1
LIM homeobox protein 1
MGI:99783

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cer1^tm1Bhr/Cer1^tm1Bhr Lhx1^tm1Bhr/Lhx1⁺ involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:62080
En1^tm2(cre)Wrst/En1⁺ Lhx1^tm1Tmj/Lhx1^tm2.1Bhr Lhx5^tm1Lmgd/Lhx5^tm1Lmgd involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ	absent Purkinje cell layer	J:123471
	decreased Purkinje cell number	J:123471
	small cerebellum	J:123471
Lhx1^tm1Bhr/Lhx1⁺ Pgap1^oto/Pgap1⁺ involves: 129S7/SvEvBrd * C57BL/6J * STOCK In(1)1Rk/J	abnormal telencephalon morphology	J:41878
Lhx1^tm1Bhr/Lhx1⁺ Pgap1^oto/Pgap1^oto involves: 129S7/SvEvBrd * C57BL/6J * STOCK In(1)1Rk/J	abnormal brain morphology	J:41878
	abnormal diencephalon morphology	J:41878
	abnormal telencephalon morphology	J:41878
Lhx1^tm1Bhr/Lhx1⁺ Ssbp3^{Tg(SOD1)1Hssk}/Ssbp3⁺ involves: 129S7/SvEvBrd * C3H/He * C57BL/6 * ICR	embryonic growth retardation	J:98485
	failure of initiation of embryo turning	J:98485
	microcephaly	J:98485
Lhx1^tm1Bhr/Lhx1^tm1Bhr Pgap1^oto/Pgap1⁺ involves: 129S7/SvEvBrd * C57BL/6J * STOCK In(1)1Rk/J	abnormal brain morphology	J:41878
	abnormal developmental patterning	J:41878
Lhx1^tm1Tmj/Lhx1⁺ Ret^tm1Kln/Ret^tm1Kln Tg(Nes-cre)1Kln/0 involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL	abnormal axon guidance	J:110955
Lhx1^tm1Tmj/Lhx1⁺ Ret^tm1.1Kln/Ret^tm1.1Kln involves: 129/Sv * BALB/c * C57BL/6 * CBA/J	abnormal axon guidance	J:110955
Lhx1^tm1Tmj/Lhx1^tm4Bhr Lhx5^tm1Lmgd/Lhx5^tm1Lmgd Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	absent cerebellar foliation	J:123471
	absent Purkinje cell layer	J:123471
	decreased Purkinje cell number	J:123471
	small cerebellum	J:123471

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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