Rab23 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rab23
RAB23, member RAS oncogene family
MGI:99833

35 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rab23^opb2/Rab23^opb2 involves: C3H/HeJ * C57BL/6J	abnormal eye morphology	J:48268
	embryonic lethality during organogenesis, incomplete penetrance	J:48268
	exencephaly	J:48268
	incomplete caudal neuropore closure	J:48268
	polydactyly	J:48268
Rab23^opb2/Rab23^opb2 involves: C3HeB/FeJ * C57BL/6J	abnormal spinal cord morphology	J:98216
	embryonic lethality during organogenesis, complete penetrance	J:98216
	exencephaly	J:98216
	polydactyly	J:98216
Rab23^opb/Rab23^opb B6.Cg-Rab23^opb	abnormal forelimb zeugopod morphology	J:42171
	abnormal hindlimb zeugopod morphology	J:42171
	abnormal neural tube morphology	J:42171
	abnormal spinal cord morphology	J:42171
	abnormal vertebral arch development	J:42171
	anophthalmia	J:42171
	exencephaly	J:42171
	open neural tube	J:42171
	skin detachment	J:42171
	spina bifida	J:42171
	spina bifida occulta	J:42171
Rab23^opb/Rab23^opb involves: C57BL/6 * NMRI	abnormal axial skeleton morphology	J:21617
	abnormal dorsal root ganglion morphology	J:21617
	abnormal hindlimb zeugopod morphology	J:21617
	abnormal lens induction	J:21617
	abnormal lens vesicle development	J:21617
	abnormal limb development	J:21617
	abnormal neural tube closure	J:21617
	abnormal neural tube ventricular layer morphology	J:21617
	abnormal optic cup morphology	J:21617
	abnormal postnatal subventricular zone morphology	J:21617
	abnormal retina neuronal layer morphology	J:21617
	abnormal spinal cord central canal morphology	J:21617
	abnormal spinal cord morphology	J:21617
	abnormal tarsal bone morphology	J:21617
	absent tibia	J:21617
	exencephaly	J:21617, J:42171
	open neural tube	J:21617
Rab23^{tm1b(EUCOMM)Wtsi}/Rab23⁺ C57BL/6N-Rab23^{tm1b(EUCOMM)Wtsi}/H	decreased bone mineral content	J:211773
	decreased lean body mass	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased mean platelet volume	J:211773
Rab23^{tm1b(EUCOMM)Wtsi}/Rab23^{tm1b(EUCOMM)Wtsi} C57BL/6N-Rab23^{tm1b(EUCOMM)Wtsi}/H	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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