Prkd1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkd1
protein kinase D1
MGI:99879

13 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkd1^{em2(IMPC)Wtsi}/Prkd1⁺ C57BL/6N-Prkd1^{em2(IMPC)Wtsi}/Wtsi	increased circulating insulin level	J:211773
	increased leukocyte cell number	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
Prkd1^tm1.1Daca/Prkd1^tm1.1Daca involves: C57BL/6	embryonic lethality during organogenesis, incomplete penetrance	J:166867
	lethality throughout fetal growth and development, incomplete penetrance	J:166867
	perinatal lethality, incomplete penetrance	J:166867
Prkd1^tm1.1Eno/Prkd1^tm1.1Eno involves: 129S/SvEv * C57BL/6	embryonic lethality, incomplete penetrance	J:132803
Prkd1^tm1Eno/Prkd1^tm1Eno Tg(Myh6-cre)2182Mds/? involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal heart left ventricle morphology	J:132803
	abnormal heart rate	J:132803
	cardiac fibrosis	J:132803
	increased cardiac muscle contractility	J:132803
	increased heart weight	J:132803

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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