Slc1a3 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
MGI:99917

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chd7^{tm2c(EUCOMM)Wtsi}/Chd7^{tm2c(EUCOMM)Wtsi} Slc1a3^{tm1(cre/ERT2)Mgoe}/Slc1a3⁺ involves: 129S2/SvPas * C57BL/6 * C57BL/6N * SJL	abnormal neuron number	J:222062
	abnormal neuronal stem cell morphology	J:222062
	decreased neuron number	J:222062
	decreased neuronal precursor cell number	J:222062
	increased neuron apoptosis	J:222062
	increased neuron number	J:222062
	increased neuronal precursor cell number	J:222062
	increased neuronal stem cell self-renewal	J:222062
Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor^tm1Sor Pten^tm1Mro/Pten^tm1Mro Slc1a3^{tm1(cre/ERT2)Mgoe}/Slc1a3⁺ Trp53^tm1Brn/Trp53^tm1Brn involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor	increased astrocytoma incidence	J:229481
	increased glioma incidence	J:229481
	increased oligodendroglioma incidence	J:229481
Ntrk2^tm2Kln/Ntrk2^tm2Kln Slc1a3^{tm1(cre/ERT2)Mgoe}/? Gt(ROSA)26Sor^tm1Sor/? involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * SJL	abnormal dendrite morphology	J:143452
	abnormal neuron differentiation	J:143452
	decreased locomotor activity	J:143452
	increased thigmotaxis	J:143452
	reduced long-term potentiation	J:143452
Ntrk2^tm2Kln/Ntrk2^tm2Kln Slc1a3^{tm1(cre/ERT2)Mgoe}/? Tg(CAG-Bgeo/GFP)21Lbe/? involves: 129/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:143452
Slc1a1^tm1Wst/Slc1a1^tm1Wst Slc1a3^tm1Wst/Slc1a3^tm1Wst involves: 129S1/Sv * 129X1/SvJ	abnormal nerve conduction	J:93201

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24