Slc1a3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
MGI:99917

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chd7^{tm2c(EUCOMM)Wtsi}/Chd7^{tm2c(EUCOMM)Wtsi} Slc1a3^{tm1(cre/ERT2)Mgoe}/Slc1a3⁺ involves: 129S2/SvPas * C57BL/6 * C57BL/6N * SJL	abnormal neuron number	J:222062
	abnormal neuronal stem cell morphology	J:222062
	decreased neuron number	J:222062
	decreased neuronal precursor cell number	J:222062
	increased neuron apoptosis	J:222062
	increased neuron number	J:222062
	increased neuronal precursor cell number	J:222062
	increased neuronal stem cell self-renewal	J:222062
Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor^tm1Sor Pten^tm1Mro/Pten^tm1Mro Slc1a3^{tm1(cre/ERT2)Mgoe}/Slc1a3⁺ Trp53^tm1Brn/Trp53^tm1Brn involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor	increased astrocytoma incidence	J:229481
	increased glioma incidence	J:229481
	increased oligodendroglioma incidence	J:229481
Ntrk2^tm2Kln/Ntrk2^tm2Kln Slc1a3^{tm1(cre/ERT2)Mgoe}/? Gt(ROSA)26Sor^tm1Sor/? involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * SJL	abnormal dendrite morphology	J:143452
	abnormal neuron differentiation	J:143452
	decreased locomotor activity	J:143452
	increased thigmotaxis	J:143452
	reduced long-term potentiation	J:143452
Ntrk2^tm2Kln/Ntrk2^tm2Kln Slc1a3^{tm1(cre/ERT2)Mgoe}/? Tg(CAG-Bgeo/GFP)21Lbe/? involves: 129/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:143452
Slc1a1^tm1Wst/Slc1a1^tm1Wst Slc1a3^tm1Wst/Slc1a3^tm1Wst involves: 129S1/Sv * 129X1/SvJ	abnormal nerve conduction	J:93201

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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