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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mybl1
myeloblastosis oncogene-like 1
MGI:99925
37 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mybl1repro9/Mybl1repro9
involves: C3HeB/FeJ * C57BL/6J 		abnormal double-strand DNA break repair J:175539
abnormal male germ cell apoptosis J:175539
abnormal synaptonemal complex J:175539
arrest of male meiosis J:175539
azoospermia J:175539
normal growth/size/body region phenotype J:175539
male infertility J:175539
normal reproductive system phenotype J:175539
small testis J:175539
Mybl1repro9/Mybl1tm1Epr
involves: C3HeB/FeJ * C57BL/6J 		abnormal synaptonemal complex J:175539
abnormal testis morphology J:175539
arrest of male meiosis J:175539
azoospermia J:175539
male infertility J:175539
Mybl1tm1.1Wtsn/Mybl1tm1.1Wtsn
involves: 129S6/SvEvTac * C57BL/6 * SJL 		no abnormal phenotype detected J:121059
Mybl1tm1Epr/Mybl1tm1Epr
involves: 129 * C57BL/6 		abnormal humoral immune response J:67604
abnormal spleen B cell follicle morphology J:67604
abnormal spleen marginal zone morphology J:67604
decreased B cell number J:67604
decreased IgG1 level J:67604
decreased IgG2a level J:67604
decreased IgG3 level J:67604
decreased spleen germinal center number J:67604
increased spleen red pulp amount J:67604
small spleen J:67604
spleen hypoplasia J:67604
Mybl1tm1Epr/Mybl1tm1Epr
Not Specified 		abnormal mammary gland epithelium morphology J:39632
abnormal mammary gland growth during lactation J:39632
abnormal mammary gland growth during pregnancy J:39632
abnormal nursing J:39632
abnormal Sertoli cell morphology J:39632
abnormal spermatocyte morphology J:39632
abnormal synaptonemal complex J:175539
arrest of male meiosis J:39632, J:175539
arrest of spermatogenesis J:39632
azoospermia J:39632, J:175539
decreased body size J:39632
decreased male germ cell number J:39632
decreased testis weight J:39632
hunched posture J:39632
increased male germ cell apoptosis J:39632
male infertility J:39632, J:175539
postnatal growth retardation J:39632
small seminiferous tubules J:39632
small testis J:39632
wrinkled skin J:39632
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory