Gja8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gja8
gap junction protein, alpha 8
MGI:99953

23 phenotypes from 11 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gja8^Aey5/Gja8⁺ C3HeB/FeJ-Gja8^Aey5	abnormal lens fiber morphology	J:74555
	cataract	J:74555
	small lens	J:74555
Gja8^Aey5/Gja8^Aey5 C3HeB/FeJ-Gja8^Aey5	abnormal lens fiber morphology	J:74555
	cataract	J:74555
	small lens	J:74555
Gja8^dcm/Gja8^dcm BALB/c-Gja8^dcm	abnormal cornea morphology	J:91434
	abnormal iris morphology	J:91434
	abnormal lens fiber morphology	J:91434
	abnormal optic stalk morphology	J:91434
	abnormal pupil morphology	J:91434
	abnormal retina morphology	J:91434
	cataract	J:91434
	increased body weight	J:91434
	microphthalmia	J:91434
Gja8^L1/Gja8⁺ involves: C3H/HeJ * C57BL/6J	abnormal lens fiber morphology	J:108522
	cataract	J:108522
	lens vacuoles	J:108522
	microphthalmia	J:108522
	ruptured lens capsule	J:108522
Gja8^L1/Gja8^L1 involves: C3H/HeJ * C57BL/6J	abnormal lens fiber morphology	J:108522
	cataract	J:108522
	lens vacuoles	J:108522
	microphthalmia	J:108522
	ruptured lens capsule	J:108522
Gja8^L1/Gja8^tm1Scr involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J	microphthalmia	J:108522
	total cataract	J:108522
	normal vision/eye phenotype	J:108522
Gja8^Lop10/Gja8⁺ C;AK-Gja8^Lop10/J	nuclear cataract	J:4160
Gja8^Lop10/Gja8^Lop10 C;AK-Gja8^Lop10/J	abnormal lens development	J:75387
	abnormal lens fiber morphology	J:75387
	cataract	J:4160, J:75387
	microphthalmia	J:4160
	ruptured lens capsule	J:75387
Gja8^Lop10/Gja8^tm1Scr involves: 129S4/SvJae * AKR/J * BALB/cJ * C57BL/6J	cataract	J:75387
	microphthalmia	J:75387
Gja8^No2/Gja8⁺ involves: 101 * C3H	nuclear cataract	J:49492
Gja8^No2/Gja8^No2 involves: 101 * C3H	nuclear cataract	J:49492
Gja8^R205G/Gja8⁺ B6.Cg-Gja8^R205G	nuclear cataract	J:195727
Gja8^R205G/Gja8⁺ B6.Cg-Gja8^R205G	small lens	J:195727
Gja8^R205G/Gja8⁺ CWXS/Agl-Gja8^R205G	nuclear cataract	J:195727
Gja8^R205G/? involves: CWD/LeAgl * SJL/J	cataract	J:156373
Gja8^R205G/? involves: CWD/LeAgl * SJL/J	microphthalmia	J:156373
Gja8^R205G/Gja8^R205G B6.Cg-Gja8^R205G	lens vacuoles	J:195727
	microphthalmia	J:195727
	nuclear cataract	J:195727
	small lens	J:195727
Gja8^R205G/Gja8^R205G CWXS/Agl-Gja8^R205G	microphthalmia	J:195727
Gja8^R205G/Gja8^R205G CWXS/Agl-Gja8^R205G	nuclear cataract	J:195727
Gja8^R205G/Gja8^R205G involves: 129S4/SvJae * CWD/LeAgl * SJL/J	abnormal lens fiber morphology	J:195727
	lens vacuoles	J:195727
	nuclear cataract	J:195727
Gja8^R205G/Gja8^tm1Scr involves: 129S1/Sv * 129X1/SvJ * CWD/LeAgl * SJL/J	microphthalmia	J:195727
	nuclear cataract	J:195727
Gja8^tm1(Gja3)Tww/Gja8^tm1(Gja3)Tww involves: 129S/SvEv	abnormal eye development	J:73875
	abnormal lens development	J:73875
	microphthalmia	J:73875
	small lens	J:73875
Gja8^{tm1b(EUCOMM)Hmgu}/Gja8^{tm1b(EUCOMM)Hmgu} C57BL/6N-Gja8^{tm1b(EUCOMM)Hmgu}/H	abnormal retina morphology	J:211773
	increased circulating amylase level	J:211773
	increased kidney weight	J:211773
Gja8^tm1Paul/Gja8^tm1Paul involves: 129S4/SvJae * C57BL/6J	abnormal eye development	J:50894
	abnormal eye morphology	J:50894
	abnormal lens development	J:50894
	abnormal lens fiber morphology	J:50894
	cataract	J:50894
	microphthalmia	J:50894
	small lens	J:50894
Gja8^tm1Rtm/Gja8^tm1Rtm involves: 129/Sv * C57BL/6	abnormal eye electrophysiology	J:106299
	abnormal eye physiology	J:106299
	abnormal lens morphology	J:106299
	cataract	J:106299

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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