Gja8 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gja8
gap junction protein, alpha 8
MGI:99953

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Crygb^S11R/Crygb^S11R Gja8^tm1(Gja3)Tww/Gja8^tm1(Gja3)Tww involves: A/J * C57BL/6J	abnormal lens morphology	J:165131
	normal vision/eye phenotype	J:165131
Gja3^tm1Scr/Gja3^tm1Scr Gja8^L1/Gja8⁺ involves: 129S4/SvJae * C3H/HeJ * C57BL/6J	abnormal lens morphology	J:108522
	nuclear cataract	J:108522
Gja3^tm1Scr/Gja3^tm1Scr Gja8^L1/Gja8^tm1Scr involves: 129 * C3H/HeJ * C57BL/6J	microphthalmia	J:108522
	nuclear cataract	J:108522
	normal vision/eye phenotype	J:108522
Gja3^tm1Scr/Gja3^tm1Scr Gja8^R205G/Gja8^R205G involves: 129S4/SvJae * CWD/LeAgl * SJL/J	nuclear cataract	J:195727
	normal vision/eye phenotype	J:195727
Gja3^tm1Scr/Gja3^tm1Scr Gja8^tm1Scr/Gja8^tm1Scr involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	microphthalmia	J:108522
	nuclear cataract	J:108522
	normal vision/eye phenotype	J:108522
Gja8^Aey69/Gja8^Aey69 H3c14^Aey69/H3c14^Aey69 C3HeB/FeJ	abnormal cornea morphology	J:277247
	abnormal lens development	J:277247
	abnormal retina morphology	J:277247
	decreased anxiety-related response	J:277247
	decreased body mass index	J:277247
	normal embryo phenotype	J:277247
	hypolipidemia	J:277247
	increased body temperature	J:277247
	increased cornea thickness	J:277247
	increased locomotor activity	J:277247
	increased vertical activity	J:277247
	microphthalmia	J:277247
	normal reproductive system phenotype	J:277247
	retina hyperplasia	J:277247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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