Ighmbp2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ighmbp2
immunoglobulin mu DNA binding protein 2
MGI:99954

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cmn1^CAST/Ei/? Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Mnm^C/Mnm^C involves: C57BL/6J * C57BLKS/J * CAST/Ei * DBA/J	dilated cardiomyopathy	J:102748
Cmn2^CAST/Ei/? Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Mnm^C/Mnm^C involves: C57BL/6J * C57BLKS/J * CAST/Ei * DBA/J	dilated cardiomyopathy	J:102748
Cmn3^C57BL/6J/? Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Mnm^C/Mnm^C involves: C57BL/6J * C57BLKS/J * CAST/Ei * DBA/J	dilated cardiomyopathy	J:102748
Cmn3^CAST/Ei/? Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Mnm^C/Mnm^C involves: C57BL/6J * C57BLKS/J * CAST/Ei * DBA/J	dilated cardiomyopathy	J:102748
Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Mnm^C/Mnm^C involves: C57BL/6J * C57BLKS/J * CAST/Ei * DBA/J	abnormal cardiovascular system physiology	J:90418
	abnormal impulse conducting system conduction	J:90418
	abnormal innervation pattern to muscle	J:51890
	decreased grip strength	J:90418
	decreased pulmonary respiratory rate	J:90418
	dilated cardiomyopathy	J:90418
	increased circulating creatine kinase level	J:90418
	motor neuron degeneration	J:90418
	muscle degeneration	J:90418
	muscular atrophy	J:51890
	pleural effusion	J:90418
	premature death	J:51890, J:90418
	prolonged P wave	J:90418
	prolonged PR interval	J:90418
	prolonged QRS complex duration	J:90418
	pulmonary edema	J:90418
	weight loss	J:90418
Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Tg(Eno2-Ighmbp2)17Cx/? Tg(Ttn-Ighmbp2)45Cx/? involves: C57BL/6J * C57BLKS/J	increased heart weight	J:102748
Ighmbp2^nmd-2J/Ighmbp2^nmd-2J Tg(Eno2-Ighmbp2)17Cx/? Tg(Ttn-Ighmbp2)108Cx/? involves: C57BL/6J * C57BLKS/J	increased heart weight	J:102748

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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