Tgfbi Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tgfbi
transforming growth factor, beta induced
MGI:99959

27 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tgfbi^em1Yaou/Tgfbi⁺ involves: C57BL/6NCr	cornea opacity	J:285437
Tgfbi^em1Yaou/Tgfbi^em1Yaou involves: C57BL/6NCr	abnormal cornea morphology	J:285437
	abnormal cornea stroma morphology	J:285437
	cornea opacity	J:285437
	delayed wound healing	J:285437
Tgfbi^tm1.1Nap/Tgfbi^tm1.1Nap B6N.129S(FVB)-Tgfbi^tm1.1Nap	abnormal retina inner nuclear layer thickness	J:230754
	decreased retina apoptosis	J:230754
	normal neoplasm	J:230754
	normal vision/eye phenotype	J:230754
Tgfbi^tm1Jwu/Tgfbi^tm1Jwu B6.129-Tgfbi^tm1Jwu	abnormal pancreatic islet morphology	J:213611
	decreased insulin secretion	J:213611
	normal endocrine/exocrine gland phenotype	J:213611
	normal growth/size/body region phenotype	J:213611
	increased pancreatic beta cell apoptosis	J:213611
	increased susceptibility to non-insulin-dependent diabetes	J:213611
Tgfbi^tm1Jwu/Tgfbi^tm1Jwu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal pancreatic beta cell physiology	J:213611
Tgfbi^tm1Zhao/Tgfbi^tm1Zhao involves: 129 * C57BL/6J	abnormal cell nucleus morphology	J:143036
	abnormal chromosome morphology	J:143036
	decreased body weight	J:143036
	enlarged spleen	J:143036
	increased B cell number	J:143036
	increased incidence of tumors by chemical induction	J:143036
	increased lung adenocarcinoma incidence	J:143036
	increased lymphoma incidence	J:143036
	increased malignant tumor incidence	J:143036
	increased tumor incidence	J:143036
	postnatal growth retardation	J:143036
	premature death	J:143036

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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