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Plcb1tm1Hssh
Targeted Allele Detail
Summary
Symbol: Plcb1tm1Hssh
Name: phospholipase C, beta 1; targeted mutation 1, Hee-Sup Shin
MGI ID: MGI:2652485
Synonyms: PLC-beta1-, PLCBeta1-
Gene: Plcb1  Location: Chr2:134628084-135317178 bp, + strand  Genetic Position: Chr2, 65.66 cM
Alliance: Plcb1tm1Hssh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43077
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details: The exon encoding amino acids 50 through 82 was disrupted by a neomycin selection cassette inserted by homologous recombination. (J:43077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 42 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plcb1 Mutation:  71 strains or lines available
References
Original:  J:43077 Kim D, et al., Phospholipase C isozymes selectively couple to specific neurotransmitter receptors. Nature. 1997 Sep 18;389(6648):290-3
All:  26 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory