MGI loads vertebrate orthology data based on the "stringent" set of homology class data from the Alliance of Genome Resources. The orthology inferences from different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT). DIOPT integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, SonicParanoid, and ZFIN. These data include human, rat, and zebrafish homologs.