MGI contains homology information for mouse, human, cattle, chick and other vertebrate organisms. A homology record shows the symbol, organism, chromosome, cM position, cytogenetic band, and accession ID for each gene in the vertebrate homology class. Available links to other resources appear as well (e.g., Entrez Gene, HGNC, Gene Tree, OMIM). See Interpreting Vertebrate Homology Class Reports for more detail.

MGI loads sequence based vertebrate homology assertions from NCBI HomoloGene. HomoloGene programmatically detects homologs among the genome features of several completely sequenced eukaryotic genomes. In addition, we continue to work with the research community to carefully curate gene family sets, usually at the instigation of the research community.