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pMH8 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pMH8
  • Sequence Type
    cDNA
  • ID
    MGI:10110
  • Region Covered
    overlapping clones MH4 and MH8, together encode 5'/3' flanking regions and the entire coding sequence
  • Insert Site
    HpaI
  • Insert Size
    ~4.5kb
  • Note
    MH8 encodes the H.1 allotype of Cfh. 5' and 3' noncoding region sequences presented.
  • Synonyms
    MH8
Source
  • Species
    mouse, laboratory
  • Strain
    B10.WR
  • Tissue
    liver
Genes
Cfh complement component factor h
Sequences
M12660 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:9230 Seldin MF, et al., Genomics. 1988 Jan;2(1):48-56
Endonuclease Gene Allele Fragments Strains
BamHI Cfh a multiple bands 129P3/J, A/He, A/J, BDP/J, BUB/BnJ, C3H/HeJ, CBA/J, CE/J, DBA/1J, DBA/2J, DD, I/LnJ, MRL/MpJ, NH, RF/J, RIIIS/J, SJL/J, SM/J, YBR/EiJ
b multiple bands ABP/LeJ, AKR/J, AL/N, BALB/c, BSVS, C57BL/6J, C57BL/10J, C57BR/cdJ, C57L/J, C58/J, HRS/J, MA/MyJ, SEA/GnJ, SEC/1ReJ, SJL/JLwPt, ST/bJ, STS/A, STS/J, SWR/J
J:9342 Seldin MF, et al., Curr Top Microbiol Immunol. 1988;137:227-32
Endonuclease Gene Allele Fragments Strains
Not Specified Cfh c not given C3H/HeJ-Faslgld/J
s not given M. spretus
J:25567 Kozak CA, et al., Genomics. 1995 Jun 10;27(3):405-11
Endonuclease Gene Allele Fragments Strains
BglII Cfh m not given M. m. musculus
n not given NFS/N
EcoRI Cfh n not given NFS/N
s not given M. spretus
References
J:8307 Kristensen T, et al., Murine protein H is comprised of 20 repeating units, 61 amino acids in length. Proc Natl Acad Sci U S A. 1986 Jun;83(11):3963-7
J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
J:9342 Seldin MF, et al., A molecular genetic approach to gld autoimmune disease. Curr Top Microbiol Immunol. 1988;137:227-32
J:10197 Natsuume-Sakai S, et al., Demonstration of an unusual allelic variation of mouse factor H by the complete cDNA sequence of the H.2 allotype. J Immunol. 1990 Jan 1;144(1):358-62
J:25567 Kozak CA, et al., Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes. Genomics. 1995 Jun 10;27(3):405-11
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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