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pHDS58 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pHDS58
  • Sequence Type
    cDNA
  • ID
    MGI:10208
  • Region Covered
    encodes Tcra-V3, Tcra-J(2c), Tcra-C gene segments, as well as 5'/3'-untranslated regions
  • Insert Site
    PstI
  • Insert Size
    1372 bp
Source
  • Species
    mouse, laboratory
  • Strain
    BALB.B
  • Tissue
    cytotoxic T-lymphocyte
  • Cell Line
    2C
Genes
Tcra-J T cell receptor alpha, joining region
Tcra-V3 T cell receptor alpha, variable 3
Trac T cell receptor alpha constant
Polymorphisms
J:8483 Berman JW, et al., Immunogenetics. 1986;24(5):328-30
Endonuclease Gene Allele Fragments Strains
EcoRI Tcra-V3 b ~18,~13,9,6.2,3.9,2.2, .9kb B10.D2-Hc0 H2d H2-T18c/oSnJ, C57BL/6J, C57BL/10J, C57BLKS, C57BR/cdJ, C57L/J, C58/J
c 20,15,9,6.2,3.9,2.2kb 129P3/J, A/J, AKR/J, B6By.C-H8c, BALB/c, C3H/J, RF/J, SJL/J
d ~20,~15,6.2,~5,3.9,2.2kb B10.D2/(57N)Sn, DBA/2J
J:10336 Crosby JL, et al., Genomics. 1990 Feb;6(2):252-9
Endonuclease Gene Allele Fragments Strains
HindIII Tcra b absent C57BL/6J
s 2.3,9.0,9.8,20.0kb M. spretus
J:10663 Eicher EM, et al., Genetics. 1990 Jun;125(2):431-46
Endonuclease Gene Allele Fragments Strains
EcoRI Tcra n 11.1,2.2kb NZB
s absent SM
References
J:7627 Saito H, et al., A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature. 1984 Nov 1-7;312(5989):36-40
J:7727 Kranz DM, et al., Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. Science. 1985 Feb 22;227(4689):941-5
J:7998 Hayday AC, et al., Unusual organization and diversity of T-cell receptor alpha-chain genes. Nature. 1985 Aug 29-Sep 4;316(6031):828-32
J:8483 Berman JW, et al., Restriction length polymorphism in the variable region of the Tcr locus linked to histocompatibility antigen H-8 on murine chromosome 14. Immunogenetics. 1986;24(5):328-30
J:10336 Crosby JL, et al., A complex of serine protease genes expressed preferentially in cytotoxic T-lymphocytes is closely linked to the T-cell receptor alpha- and delta-chain genes on mouse chromosome 14. Genomics. 1990 Feb;6(2):252-9
J:10663 Eicher EM, et al., The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics. 1990 Jun;125(2):431-46
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