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MRL-DNA4 Probe Detail
Nucleotide
Probe/Clone
  • Name
    MRL-DNA4
  • Sequence Type
    cDNA
  • ID
    MGI:10544
Source
  • Species
    mouse, laboratory
  • Strain
    MRL-Fas
  • Cell Line
    hybridoma cell line MRL-RF12
Genes
Igh-D immunoglobulin heavy chain diversity region
Igh-J immunoglobulin heavy chain, joining region
Igh-V10 immunoglobulin heavy chain (V10 family)
Polymorphisms
J:9193 Kofler R, J Immunol. 1988 Jun 1;140(11):4031-4
Endonuclease Gene Allele Fragments Strains
BamHI Igh-V10 a 11,9,6.5kb BALB/c
b 6.5,2.8kb C57BL/6
c 11,9.5,8,1.7,1.2kb DBA/2
d 9,2.5,1.7,1.2kb AKR/N
e 12,2.8,1.3kb A/J
j 9,2.5,1.7,1.2kb C3H/St
EcoRI Igh-V10 a 9,8,6kb BALB/c
b 12,6.1,5,4.1kb C57BL/6
c 9,8,6kb DBA/2
d 8,6,4.8,4kb AKR/N
e 12,7kb A/J
j 8,6,4.8,4kb C3H/St
HindIII Igh-V10 a 8,6,3kb BALB/c
b 6,2kb C57BL/6
c 3,1.5kb DBA/2
d 3,2,1.5kb AKR/N
e 3,1.5kb A/J
j 3,2,1.5kb C3H/St
PstI Igh-V10 a 6,4.5,1.5kb BALB/c
b 6,4.5kb C57BL/6
c 8,4.6,4.7kb DBA/2
d 7,4.5,1.5kb AKR/N
e 4.8,5kb A/J
j 7,4.5,1.5kb C3H/St
References
J:9193 Kofler R, A new murine Ig VH gene family. J Immunol. 1988 Jun 1;140(11):4031-4
J:52274 Whitcomb EA, et al., Germline structure and differential utilization of Igha and Ighb VH10 genes. J Immunol. 1999 Feb 1;162(3):1541-50

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory