About   Help   FAQ
MMTV-LTR Probe Detail
Nucleotide
Probe/Clone
  • Name
    MMTV-LTR
  • Sequence Type
    genomic
  • ID
    MGI:10562
  • Region Covered
    PstI fragment covering full LTR of MTV(GR40)
  • Insert Site
    PstI
  • Insert Size
    1.4kb
  • Synonyms
    MMTV LTR, MMTV LTR probe
Source
  • Species
    mouse, laboratory
  • Tissue Description
    MMTV provirus
Genes
Mtv1 mammary tumor virus locus 1
Mtv11 mammary tumor virus locus 11
Mtv13 mammary tumor virus locus 13
Mtv14 mammary tumor virus locus 14
Mtv17 mammary tumor virus locus 17
Mtv3 mammary tumor virus locus 3
Mtv38 mammary tumor virus locus 38
Mtv42 mammary tumor virus locus 42
Mtv50 mammary tumor virus locus 50
Mtv6 mammary tumor virus locus 6
Mtv7 mammary tumor virus locus 7
Mtv8 mammary tumor virus locus 8
Mtv9 mammary tumor virus locus 9
Mtv55 mammary tumor virus locus 55
Polymorphisms
J:8083 Michalides R, et al., Virology. 1985 Apr 30;142(2):278-90
Notes: MMTV probes recognise multiple Mtv loci, therefore additional fragments are observed.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv3 a 21.0,7.0,1.0kb STS/A
b absent BALB/cHeA
EcoRI Mtv7 a 16.7,13.0kb STS/A
b absent BALB/cHeA
EcoRI Mtv8 a 8.5,6.7kb BALB/cHeA, STS/A
EcoRI Mtv9 a 10.0,7.8kb BALB/cHeA
b absent STS/A
EcoRI Mtv17 a 10.6,8.7kb STS/A
b absent BALB/cHeA
J:8666 Reeves RH, et al., Cytogenet Cell Genet. 1987;44(2-3):76-81
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv6 a 16kb BALB/cPt
c absent CZECHII
J:10908 Shaper NL, et al., Cytogenet Cell Genet. 1990;54(3-4):172-4
Notes: A 1.4 kb PstI fragment of MMTV-C3H was used as the hybridization probe.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv13 m absent M. m. musculus
n 9.0,5.8kb NFS/N
EcoRI Mtv14 m absent M. m. musculus
n 1.7kb NFS/N
EcoRI Mtv17 m absent M. m. musculus
n 10.0,8.3kb NFS/N
J:11092 Nishikawa R, et al., Lab Anim. 1991 Jan;25(1):4-8
Notes: Mtv-42 is on the Y chromosome, therefore the restriction fragments listed appear only in males.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv42 a 15.0kb DD/Tbr, NFS, NIH Swiss, STS/A
b absent BALB/cHeA, C3H/HeNJcl, C57BL/6NJcl, CBA/JJcl, SHN/Mei, SLN
J:11471 Moore SK, et al., Genomics. 1991 Aug;10(4):1019-29
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv14 m not given M. m. musculus
n not given AKR/J, C58/J, NFS/N
EcoRI Mtv17 m not given M. m. musculus
n not given AKR/J, C58/J, NFS/N
J:17766 Foo-Phillips M, et al., J Immunol. 1992 Dec 1;149(11):3440-7
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv1 a ~6.7,~3.0kb C3H/HeJ
b absent C57BL/6
EcoRI Mtv3 a ~19.4,~7.0kb C58/J
b absent A/J, CBA/CaH
EcoRI Mtv6 a ~17.0kb A/J, C3H/HeJ
b absent C57BL/6, C58/J, CBA/CaH
EcoRI Mtv7 a ~18.0,~12.5kb C58/J
b absent A/J, CBA/CaH
EcoRI Mtv8 a ~8.2,~6.7kb A/J, C3H/HeJ, C57BL/6, CBA/CaH
b absent C58/J
EcoRI Mtv9 a ~10.0,~8.0kb C57BL/6, CBA/CaH
b absent A/J, C3H/HeJ, C58/J
EcoRI Mtv11 a ~16.5,~5.0kb C3H/HeJ
b absent C57BL/6
EcoRI Mtv13 a ~9.4,5.0kb A/J
b absent C58/J, CBA/CaH
EcoRI Mtv14 a ~1.0kb C3H/HeJ, CBA/CaH
b absent A/J, C58/J
EcoRI Mtv17 a ~11.0,~8.5kb C57BL/6, C58/J
b absent A/J, C3H/HeJ, CBA/CaH
EcoRI Mtv50 a ~12.5,3.0kb A/J
b absent C58/J, CBA/CaH
J:4958 Taylor BA, et al., Genomics. 1993 May;16(2):380-94
Endonuclease Gene Allele Fragments Strains
PvuII Mtv3 c absent CAST/EiJ
m 11.0,7.4kb MEV/Ty
PvuII Mtv7 c absent CAST/EiJ
m 17.0,2.5kb MEV/Ty
PvuII Mtv8 c absent CAST/EiJ
m 16.0,5.0kb MEV/Ty
PvuII Mtv17 c absent CAST/EiJ
m 9.8,8.0kb MEV/Ty
J:27401 Miyazaki S, et al., Genomics. 1995 Jun 10;27(3):420-4
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv38 n not given C58/J, NFS/N
s not given M. spretus
References
J:8083 Michalides R, et al., Characterization and chromosomal distribution of endogenous mouse mammary tumor viruses of European mouse strains STS/A and GR/A. Virology. 1985 Apr 30;142(2):278-90
J:8666 Reeves RH, et al., Genetic mapping of Prm-1, Igl-1, Smst, Mtv-6, Sod-1, and Ets-2 and localization of the Down syndrome region on mouse chromosome 16. Cytogenet Cell Genet. 1987;44(2-3):76-81
J:10908 Shaper NL, et al., Localization of the gene for beta 1,4-galactosyltransferase to a position in the centromeric region of mouse chromosome 4. Cytogenet Cell Genet. 1990;54(3-4):172-4
J:11092 Nishikawa R, et al., Incomplete proviral genome of mouse mammary tumour virus is present on chromosome Y of NIH Swiss and some genetically related mouse strains. Lab Anim. 1991 Jan;25(1):4-8
J:11405 Shapiro M, et al., Genetic mapping in the mouse of four loci related to the jun family of transcriptional activators. Somat Cell Mol Genet. 1991 Jul;17(4):341-7
J:11471 Moore SK, et al., Mapping of the mouse 86-kDa heat-shock protein expressed gene (Hsp86-1) on chromosome 12 and related genes on chromosomes 3, 4, 9, and 11. Genomics. 1991 Aug;10(4):1019-29
J:17766 Foo-Phillips M, et al., Characterization of the Mlsf system. II. Identification of mouse mammary tumor virus proviruses involved in the clonal deletion of self-Mlsf-reactive T cells. J Immunol. 1992 Dec 1;149(11):3440-7
J:4958 Taylor BA, et al., The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock. Genomics. 1993 May;16(2):380-94
J:27401 Miyazaki S, et al., The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics. 1995 Jun 10;27(3):420-4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory