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MMTV-LTR Probe Detail
Nucleotide
Probe/Clone
  • Name
    MMTV-LTR
  • Sequence Type
    genomic
  • ID
    MGI:10562
  • Region Covered
    PstI fragment covering full LTR of MTV(GR40)
  • Insert Site
    PstI
  • Insert Size
    1.4kb
  • Synonyms
    MMTV LTR, MMTV LTR probe
Source
  • Species
    mouse, laboratory
  • Tissue Description
    MMTV provirus
Genes
Mtv1 mammary tumor virus locus 1
Mtv11 mammary tumor virus locus 11
Mtv13 mammary tumor virus locus 13
Mtv14 mammary tumor virus locus 14
Mtv17 mammary tumor virus locus 17
Mtv3 mammary tumor virus locus 3
Mtv38 mammary tumor virus locus 38
Mtv42 mammary tumor virus locus 42
Mtv50 mammary tumor virus locus 50
Mtv6 mammary tumor virus locus 6
Mtv7 mammary tumor virus locus 7
Mtv8 mammary tumor virus locus 8
Mtv9 mammary tumor virus locus 9
Mtv55 mammary tumor virus locus 55
Polymorphisms
J:8083 Michalides R, et al., Virology. 1985 Apr 30;142(2):278-90
Notes: MMTV probes recognise multiple Mtv loci, therefore additional fragments are observed.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv3 a 21.0,7.0,1.0kb STS/A
b absent BALB/cHeA
EcoRI Mtv7 a 16.7,13.0kb STS/A
b absent BALB/cHeA
EcoRI Mtv8 a 8.5,6.7kb BALB/cHeA, STS/A
EcoRI Mtv9 a 10.0,7.8kb BALB/cHeA
b absent STS/A
EcoRI Mtv17 a 10.6,8.7kb STS/A
b absent BALB/cHeA
J:8666 Reeves RH, et al., Cytogenet Cell Genet. 1987;44(2-3):76-81
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv6 a 16kb BALB/cPt
c absent CZECHII
J:10908 Shaper NL, et al., Cytogenet Cell Genet. 1990;54(3-4):172-4
Notes: A 1.4 kb PstI fragment of MMTV-C3H was used as the hybridization probe.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv13 m absent M. m. musculus
n 9.0,5.8kb NFS/N
EcoRI Mtv14 m absent M. m. musculus
n 1.7kb NFS/N
EcoRI Mtv17 m absent M. m. musculus
n 10.0,8.3kb NFS/N
J:11092 Nishikawa R, et al., Lab Anim. 1991 Jan;25(1):4-8
Notes: Mtv-42 is on the Y chromosome, therefore the restriction fragments listed appear only in males.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv42 a 15.0kb DD/Tbr, NFS, NIH Swiss, STS/A
b absent BALB/cHeA, C3H/HeNJcl, C57BL/6NJcl, CBA/JJcl, SHN/Mei, SLN
J:11471 Moore SK, et al., Genomics. 1991 Aug;10(4):1019-29
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv14 m not given M. m. musculus
n not given AKR/J, C58/J, NFS/N
EcoRI Mtv17 m not given M. m. musculus
n not given AKR/J, C58/J, NFS/N
J:17766 Foo-Phillips M, et al., J Immunol. 1992 Dec 1;149(11):3440-7
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv1 a ~6.7,~3.0kb C3H/HeJ
b absent C57BL/6
EcoRI Mtv3 a ~19.4,~7.0kb C58/J
b absent A/J, CBA/CaH
EcoRI Mtv6 a ~17.0kb A/J, C3H/HeJ
b absent C57BL/6, C58/J, CBA/CaH
EcoRI Mtv7 a ~18.0,~12.5kb C58/J
b absent A/J, CBA/CaH
EcoRI Mtv8 a ~8.2,~6.7kb A/J, C3H/HeJ, C57BL/6, CBA/CaH
b absent C58/J
EcoRI Mtv9 a ~10.0,~8.0kb C57BL/6, CBA/CaH
b absent A/J, C3H/HeJ, C58/J
EcoRI Mtv11 a ~16.5,~5.0kb C3H/HeJ
b absent C57BL/6
EcoRI Mtv13 a ~9.4,5.0kb A/J
b absent C58/J, CBA/CaH
EcoRI Mtv14 a ~1.0kb C3H/HeJ, CBA/CaH
b absent A/J, C58/J
EcoRI Mtv17 a ~11.0,~8.5kb C57BL/6, C58/J
b absent A/J, C3H/HeJ, CBA/CaH
EcoRI Mtv50 a ~12.5,3.0kb A/J
b absent C58/J, CBA/CaH
J:4958 Taylor BA, et al., Genomics. 1993 May;16(2):380-94
Endonuclease Gene Allele Fragments Strains
PvuII Mtv3 c absent CAST/EiJ
m 11.0,7.4kb MEV/Ty
PvuII Mtv7 c absent CAST/EiJ
m 17.0,2.5kb MEV/Ty
PvuII Mtv8 c absent CAST/EiJ
m 16.0,5.0kb MEV/Ty
PvuII Mtv17 c absent CAST/EiJ
m 9.8,8.0kb MEV/Ty
J:27401 Miyazaki S, et al., Genomics. 1995 Jun 10;27(3):420-4
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv38 n not given C58/J, NFS/N
s not given M. spretus
References
J:8083 Michalides R, et al., Characterization and chromosomal distribution of endogenous mouse mammary tumor viruses of European mouse strains STS/A and GR/A. Virology. 1985 Apr 30;142(2):278-90
J:8666 Reeves RH, et al., Genetic mapping of Prm-1, Igl-1, Smst, Mtv-6, Sod-1, and Ets-2 and localization of the Down syndrome region on mouse chromosome 16. Cytogenet Cell Genet. 1987;44(2-3):76-81
J:10908 Shaper NL, et al., Localization of the gene for beta 1,4-galactosyltransferase to a position in the centromeric region of mouse chromosome 4. Cytogenet Cell Genet. 1990;54(3-4):172-4
J:11092 Nishikawa R, et al., Incomplete proviral genome of mouse mammary tumour virus is present on chromosome Y of NIH Swiss and some genetically related mouse strains. Lab Anim. 1991 Jan;25(1):4-8
J:11405 Shapiro M, et al., Genetic mapping in the mouse of four loci related to the jun family of transcriptional activators. Somat Cell Mol Genet. 1991 Jul;17(4):341-7
J:11471 Moore SK, et al., Mapping of the mouse 86-kDa heat-shock protein expressed gene (Hsp86-1) on chromosome 12 and related genes on chromosomes 3, 4, 9, and 11. Genomics. 1991 Aug;10(4):1019-29
J:17766 Foo-Phillips M, et al., Characterization of the Mlsf system. II. Identification of mouse mammary tumor virus proviruses involved in the clonal deletion of self-Mlsf-reactive T cells. J Immunol. 1992 Dec 1;149(11):3440-7
J:4958 Taylor BA, et al., The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock. Genomics. 1993 May;16(2):380-94
J:27401 Miyazaki S, et al., The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics. 1995 Jun 10;27(3):420-4
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