About   Help   FAQ
Hmgcr cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Hmgcr cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:10776
  • Region Covered
    full-length cDNA
  • Insert Size
    3.5kb
Source
  • Species
    mouse, laboratory
  • Strain
    (C57BL/6J x BALB/c)F1
Genes
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Polymorphisms
J:1025 Hwa JJ, et al., J Lipid Res. 1992 May;33(5):711-25
Notes: A 3.5kb EcoRI fragment was isolated and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
PstI Hmgcr a 5.6,4.0,2.8,2.4,1.6,1.2kb 129P3/J, AKR/J, C3H/HeJ, NZB/BlNJ, SWR/J
b 5.6,4.0,2.8,2.4,1.2,0.6kb BALB/cJ, C57BL/6J, C57L/J, C58/J, DBA/2J
PvuII Hmgcr a 6.7,4.0,3.4,3.0,0.9kb 129P3/J, AKR/J, C3H/HeJ, NZB/BlJ, SWR/J
b 6.7,4.4,4.0,3.4,3.0kb BALB/cJ, C57BL/6J, C57L/J, C58/J, DBA/2J
J:15132 Xia YR, et al., Genomics. 1993 Oct;18(1):126-30
Endonuclease Gene Allele Fragments Strains
Not Specified Hmgcr b not given C57BL/6J
s not given M. spretus
References
J:10019 Sundaresan S, et al., Genes for HMG-CoA reductase and serotonin 1a receptor are on mouse chromosome 13. Somat Cell Mol Genet. 1989 Sep;15(5):465-9
J:1025 Hwa JJ, et al., Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J Lipid Res. 1992 May;33(5):711-25
J:15132 Xia YR, et al., Chromosomal organization of mammalian POU domain factors. Genomics. 1993 Oct;18(1):126-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory