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Hmgcr cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Hmgcr cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:10776
  • Region Covered
    full-length cDNA
  • Insert Size
    3.5kb
Source
  • Species
    mouse, laboratory
  • Strain
    (C57BL/6J x BALB/c)F1
Genes
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Polymorphisms
J:1025 Hwa JJ, et al., J Lipid Res. 1992 May;33(5):711-25
Notes: A 3.5kb EcoRI fragment was isolated and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
PstI Hmgcr a 5.6,4.0,2.8,2.4,1.6,1.2kb 129P3/J, AKR/J, C3H/HeJ, NZB/BlNJ, SWR/J
b 5.6,4.0,2.8,2.4,1.2,0.6kb BALB/cJ, C57BL/6J, C57L/J, C58/J, DBA/2J
PvuII Hmgcr a 6.7,4.0,3.4,3.0,0.9kb 129P3/J, AKR/J, C3H/HeJ, NZB/BlJ, SWR/J
b 6.7,4.4,4.0,3.4,3.0kb BALB/cJ, C57BL/6J, C57L/J, C58/J, DBA/2J
J:15132 Xia YR, et al., Genomics. 1993 Oct;18(1):126-30
Endonuclease Gene Allele Fragments Strains
Not Specified Hmgcr b not given C57BL/6J
s not given M. spretus
References
J:10019 Sundaresan S, et al., Genes for HMG-CoA reductase and serotonin 1a receptor are on mouse chromosome 13. Somat Cell Mol Genet. 1989 Sep;15(5):465-9
J:1025 Hwa JJ, et al., Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J Lipid Res. 1992 May;33(5):711-25
J:15132 Xia YR, et al., Chromosomal organization of mammalian POU domain factors. Genomics. 1993 Oct;18(1):126-30

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory