About   Help   FAQ
TA28 Probe Detail
Nucleotide
Probe/Clone
  • Name
    TA28
  • Sequence Type
    cDNA
  • ID
    MGI:11517
  • Region Covered
    encodes Tcra-V4.1, Tcra-J, Tcra-C gene segments
  • Vector Type
    Phage
  • Note
    Insert subcloned from a [l]gt10 vector.
Source
  • Species
    mouse, laboratory
  • Strain
    C57BL/Ka
  • Tissue
    thymus
Genes
Tcra-J T cell receptor alpha, joining region
Tcra-V4 T cell receptor alpha, variable 4
Trac T cell receptor alpha constant
Sequences
X02931 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7997 Arden B, et al., Nature. 1985 Aug 29-Sep 4;316(6031):783-7
Endonuclease Gene Allele Fragments Strains
BamHI Tcra-V4 a multiple AKR/J, BALB/c, CBA/J
b multiple C57BL/6J
EcoRI Tcra-V4 a multiple AKR/J, BALB/c, CBA/J
b multiple C57BL/6J
HindIII Tcra-V4 a multiple AKR/J, BALB/c, CBA/J
b multiple C57BL/6J
J:9665 Klotz JL, et al., Immunogenetics. 1989;29(3):191-201
Notes: Tcra-V alleles are haplotypes. Each type (a,b,c,d) can be distinguished using BamHI or EcoRI by any of the Tcra-V probes, pUCV[a]1, pUCV[a]2, TA26, TA28, pUCV[a]5, pUCV[a]7, TA61, pUCV[a]9 or pUC2B4.
Endonuclease Gene Allele Fragments Strains
BamHI Tcra-V4 a multiple BALB/cJ, MRL
b multiple BXSB/MpJ, C57BL/6J, C58/J
b' multiple C57BL/10SnJ
c multiple NZB, SJL/J, SWR/J
d multiple NZW
Not Specified Tcra-V4 a n/a A/J, AKR/J, BALB/cJ, C3H/HeJ, CBA/J, LG/J, MRL, SB/LeJ
b n/a BXSB/MpJ, C57BL/6J, C57BL/10J, C57BL/10SnJ, C57BL/Ka, C57BR/cdJ, C57L/J, C58/J
c n/a NZB, SJL/J, SWR/J
d n/a NZW
References
J:7997 Arden B, et al., Diversity and structure of genes of the alpha family of mouse T-cell antigen receptor. Nature. 1985 Aug 29-Sep 4;316(6031):783-7
J:9665 Klotz JL, et al., Restriction fragment length polymorphisms of the mouse T-cell receptor gene families [published erratum appears in Immunogenetics 1989;30(3):235]. Immunogenetics. 1989;29(3):191-201
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory