VhARS Probe Detail MGI Mouse MGI:11827

VhARS Probe Detail

Name

VhARS
Sequence Type

cDNA
ID

MGI:11827
Region Covered

encodes Igh-VJ558 gene segment VhARS, Igh-D, Igh-J (J2) and Igh-4 gene segments
Child Clones

CDR-1 probe, CDR-2 probe, VHA probe
Vector Type

Plasmid
Insert Site

BamHI
Synonyms

93G7

Species

mouse, laboratory
Strain

A/J
Cell Line

hybridoma cell line 93G7

Ighg1	immunoglobulin heavy constant gamma 1 (G1m marker)
Igh-D	immunoglobulin heavy chain diversity region
Igh-J	immunoglobulin heavy chain, joining region
Igh-VJ558	immunoglobulin heavy chain (J558 family)

J:6725 Sims J, et al., Science. 1982 Apr 16;216(4543):309-11

Notes: A PstI subfragment of 93G7 specific for the V gene segment was used in Southern analysis. It was noted that similar fragment sizes were observed when the entire 93G7 insert was utilized.

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	Igh-VJ558	a	multiple	A/J
BamHI	Igh-VJ558	b	multiple	BALB/c
EcoRI	Igh-VJ558	a	multiple	A/J
EcoRI	Igh-VJ558	b	multiple	BALB/c

J:6725 Sims J, et al., Somatic mutation in genes for the variable portion of the immunoglobulin heavy chain. Science. 1982 Apr 16;216(4543):309-11

J:7612 Brodeur PH, et al., The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes. Eur J Immunol. 1984 Oct;14(10):922-30

J:9401 Rathbun GA, et al., Molecular characterization of the A/J J558 family of heavy chain variable region gene segments. J Mol Biol. 1988 Aug 5;202(3):383-95

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