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p-alpha-psi4 Probe Detail
Nucleotide
Probe/Clone
  • Name
    p-alpha-psi4
  • Sequence Type
    genomic
  • ID
    MGI:11840
  • Region Covered
    encodes the Hba-ps4 pseudogene and flanking sequences
  • Parent Clone
    phage clone 1
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI
  • Insert Size
    2.4kb
  • Synonyms
    alpha-psi4, alpha-psi-4
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
Genes
Hba-ps4 hemoglobin alpha, pseudogene 4
Polymorphisms
J:7337 Fox HS, et al., Immunogenetics. 1984;19(2):125-30
Notes: Proximal partial t haplotypes are associated with one of the wild-type alleles. t is null for Hba-ps4 (deleted).
Endonuclease Gene Allele Fragments Strains
TaqI Hba-ps4 b 3.4kb BALB/cJ, C57BL/6J, C58/J, DBA/1J, DBA/2J, LG/J, NZB/BlNJ, SWR/J
c 3.8,1.4kb 129/Sv, C3H/HeJ, LT/ChRe
o absent STOCK th20
t 5.2kb STOCK th17, STOCK th18, STOCK tLub2, STOCK tTu2
J:8526 Mann EA, et al., Genetics. 1986 Nov;114(3):993-1006
Notes: Using TaqI (D'Eustachio et al, J Exp Med 1984; 159:958) produces a different RFLP pattern where b and d alleles are classified as "b" and where SM/J produces a unique pattern called "c".
Endonuclease Gene Allele Fragments Strains
MspI Hba-ps4 a 6.7,6.2kb 129P3/J, AKR/J, AU/SsJ, BALB/cByJ, C3H/HeJ, C3HeB/FeJ, CBA/CaJ, DW/J, FS/EiJ, LP/J, SEC/1ReJ, YBR/Ki
b 11.8,11.1kb ABP/LeJ, BUB/BnJ, C57BL/6J, C57BL/10J, C57L/J, C58/J, LG/J, NZB/BlNJ, PL/J, SM/J, SWR/J
d 10.9kb A/J, BDP/J, C57BLKS/J, CE/J, DBA/1J, DBA/1Spr, DBA/2DeJ, DBA/2J, I/LnJ, MA/MyJ, P/J, RF/J, SB/LeJ, SJL/J, ST/bJ, WB/ReJ
J:9170 Delarbre C, et al., Mol Biol Evol. 1988 Mar;5(2):120-33
Endonuclease Gene Allele Fragments Strains
BglII Hba-ps4 a 3.5kb BTBRTF, STOCK T Itpr3tf/J, WLA76
b 8.6kb M. m. castaneus, M. m. molossinus, STOCK twPas3
c 8.6,3.5kb STOCK T/tw5, STOCK T/tw73
TaqI Hba-ps4 a 3.8,1.4kb 129/Sv
b 3.4kb BALB/c, BTBRTF, DBA/1, DBA/2, DBV, M. m. castaneus, NZB, SJL/J, STOCK T Itpr3tf/J, STOCK twPas2, WLA76
c 5.2,3.4kb STOCK T/tLub1, STOCK T/tw5, STOCK T/tw32, STOCK T/twPas1, STOCK twPas3
d 5.2kb STOCK twPas3
e 1.8,1.4kb M. m. molossinus, M. spretus
J:9310 Forejt J, et al., Genet Res. 1988 Apr;51(2):111-9
Endonuclease Gene Allele Fragments Strains
TaqI Hba-ps4 a 5.2kb C3.tw12, STOCK tp4, STOCK tp12, STOCK tp14
b 1.4,3.8kb 129
c 1.4,1.9kb PWK
J:10943 Washburn LL, et al., Genet Res. 1990 Oct-Dec;56(2-3):185-91
Notes: Multiple fragments are detected with probe [a]-[y]4. Sizes previously reported for b allele = 3.1 kb and for a allele = 3.5 kb (J Exp Med 1984; 159:958).
Endonuclease Gene Allele Fragments Strains
TaqI Hba-ps4 a 3.7kb C3H/HeSnJ
b 3.4kb C57BL/6J
J:11045 Nadeau JH, et al., Genomics. 1991 Jan;9(1):78-89
Notes: Only the size of the restriction fragments segregating and used for mapping are given.
Endonuclease Gene Allele Fragments Strains
TaqI Hba-ps4 b not given C57BL/6J
s 1.5,2.0kb M. spretus
J:31802 Gregorova S, et al., Mamm Genome. 1996 Feb;7(2):107-13
Endonuclease Gene Allele Fragments Strains
TaqI Hba-ps4 b not given C57BL/10SnPh-T
c not given C3H/DiPh
References
J:6586 Leder A, et al., Dispersion of alpha-like globin genes of the mouse to three different chromosomes. Nature. 1981 Sep 17-23;293(5829):196-200
J:7337 Fox HS, et al., An alpha globin pseudogene is located within the mouse t complex. Immunogenetics. 1984;19(2):125-30
J:8526 Mann EA, et al., Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone. Genetics. 1986 Nov;114(3):993-1006
J:9170 Delarbre C, et al., Phylogenetic distribution in the genus Mus of t-complex-specific DNA and protein markers: inferences on the origin of t-haplotypes. Mol Biol Evol. 1988 Mar;5(2):120-33
J:9310 Forejt J, et al., Three new t-haplotypes of Mus musculus reveal structural similarities to t-haplotypes of Mus domesticus. Genet Res. 1988 Apr;51(2):111-9
J:10943 Washburn LL, et al., Inheritance of T-associated sex reversal in mice. Genet Res. 1990 Oct-Dec;56(2-3):185-91
J:11045 Nadeau JH, et al., Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci. Genomics. 1991 Jan;9(1):78-89
J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
J:31802 Gregorova S, et al., Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene. Mamm Genome. 1996 Feb;7(2):107-13
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