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pVR130 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pVR130
  • Sequence Type
    genomic
  • ID
    MGI:11851
  • Region Covered
    encodes most of the Igh-VJ558 gene segment VH36-65
  • Parent Clone
  • Vector Type
    Plasmid
  • Insert Site
    BamHI
  • Insert Size
    133 bp
  • Synonyms
    V probe
Source
  • Species
    mouse, laboratory
  • Strain
    A/J
  • Cell Line
    hybridoma cell line 36-65
Genes
Igh-VJ558 immunoglobulin heavy chain (J558 family)
Polymorphisms
J:6986 Siekevitz M, et al., Eur J Immunol. 1982 Dec;12(12):1023-32
Notes: The intensity of the 6.4 kb band in the allele 'a' strains varies widely and all strains demonstrated multiple weakly hybridizing bands.
Endonuclease Gene Allele Fragments Strains
EcoRI Igh-VJ558 a 6.4kb A/J, AL/N, B10.A-H2a, BALB/c, C.AL-20, CBA-Ighb, DBA/2
b absent AKR, CBA/Tuf, NZB
References
J:6986 Siekevitz M, et al., The genetic basis of antibody production: the dominant anti-arsonate idiotype response of the strain A mouse. Eur J Immunol. 1982 Dec;12(12):1023-32
J:7008 Siekevitz M, et al., The genetic basis of antibody production: a single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse. Eur J Immunol. 1983 Feb;13(2):123-32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory