pS107V1 Probe Detail MGI Mouse MGI:11889

pS107V1 Probe Detail

Name

pS107V1
Sequence Type

cDNA
ID

MGI:11889
Region Covered

encodes 5' untranslated region, the Igh-VS107 gene segment VH107, an Igh-D (DFL16 type) gene segment and the 5' portion of a Igh-J (J1) gene segment
Parent Clone

p107-alpha-R5
Vector Type

Plasmid
Insert Site

PstI
Insert Size

445 bp
Synonyms

p107V1

Species

mouse, laboratory
Strain

BALB/c
Tissue

plasma cell
Cell Line

plasmacytoma cell line S107

Igh-D	immunoglobulin heavy chain diversity region
Igh-J	immunoglobulin heavy chain, joining region
Igh-VS107	immunoglobulin heavy chain (S107 family)

J:7909 Kofler R, et al., J Exp Med. 1985 Jul 1;162(1):346-51

Endonuclease	Gene	Allele	Fragments	Strains
HindIII	Igh-VS107	a	multiple	BALB/c
		b	multiple	B6.MRL-Fas^lpr, C57BL/6, SB/LeJ
		c	multiple	DBA/2
		d	multiple	AK.MRL-Fas^lpr, AKR, NZB
		e	multiple	A/J
		j	multiple	C3.MRL-Fas^lpr, C3H/He, CBA, LG, MRL, MRL-Fas^lpr

J:9194 Hilbert DM, et al., J Immunol. 1988 Jun 15;140(12):4364-71

Endonuclease	Gene	Allele	Fragments	Strains
EcoRI	Igh-VS107	b	2.7,3.4,5.7,7.8kb	BALB/c
EcoRI	Igh-VS107	c	2.7,4.7,5.7,7.8kb	CLA2/Cn

J:6321 Early P, et al., An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell. 1980 Apr;19(4):981-92

J:6569 Crews S, et al., A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody. Cell. 1981 Jul;25(1):59-66

J:7109 Kraig E, et al., T and B cells that recognize the same antigen do not transcribe similar heavy chain variable region gene segments. J Exp Med. 1983 Jul 1;158(1):192-209

J:7110 Kronenberg M, et al., Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts. J Exp Med. 1983 Jul 1;158(1):210-27

J:7909 Kofler R, et al., Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism. J Exp Med. 1985 Jul 1;162(1):346-51

J:9194 Hilbert DM, et al., Characterization of an inbred mouse exhibiting low responsiveness to phosphorylcholine. Antibodies from low-responder mice suggest gene conversion events within the S107VH gene family. J Immunol. 1988 Jun 15;140(12):4364-71

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