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pRS48 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pRS48
  • Sequence Type
    cDNA
  • ID
    MGI:11892
  • Region Covered
    most of the coding region, 0.13kb 3' untranslated, poly A tail
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    0.43kb
Source
  • Species
    mouse, laboratory
  • Strain
    Swiss
  • Sex
    Male
  • Tissue
    liver
  • Tissue Description
    endotoxin-induced liver
Genes
Saa serum amyloid A cluster
Saa1 serum amyloid A 1
Saa2 serum amyloid A 2
Saa3 serum amyloid A 3
Sequences
M25467 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
X03479 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7560 Taylor BA, et al., Mol Gen Genet. 1984;195(3):491-9
Endonuclease Gene Allele Fragments Strains
BamHI Saa1 a 10.5,7.2,5.9,2.8,1.3kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CBA/CaJ, CBA/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, LG/J, LP/J, MA/MyJ, NZB/BlNJ, PL/J, RF/J, RIIIS/J, SEC/1ReJ, SF/CamEiJ, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 9.4,7.2,5.9,2.8,1.4kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, I/LnJ, P/J, PRO/1ReJ, SJL/J
c 10.5,7.2,5.9,2.8,1.4kb IS/Cam, PERA
d 10.5,7.2,6.2,2.8,1.4kb SK/Cam
e 10.5,7.2,5.9,2.9,1.4kb CE/J
f 12.0,7.2,6.8,5.9,2.8,1.4 kb CAST/EiJ
g 10.5,7.2,6.8,5.9,2.8,1.4 kb MOLF/EiJ
BclI Saa1 a 20,8.0,0.7kb C57BL/10Sn
b 8.0,6.0,4.4,0.7kb B10.129-SelenosH47-b/(21M)Sn
c 8.0,3.8,2.3,0.7kb IS/Cam
BglII Saa1 a,c 15.0,4.7,4.0kb C57BL/10Sn, IS/Cam
b 9.4,4.7,4.0kb B10.129-SelenosH47-b/(21M)Sn
EcoRI Saa1 a 7.0,6.0,4.4,2.9kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CBA/CaJ, CBA/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, LG/J, LP/J, MA/MyJ, NZB/BlNJ, PL/J, RF/J, SEC/1ReJ, SF/CamEiJ, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 7.0,4.4,2.9kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, CAST/EiJ, CE/J, I/LnJ, IS/Cam, MOLF/EiJ, P/J, PERA, PRO/1ReJ, RIIIS/J, SJL/J, SK/Cam
HindIII Saa1 a 10.0,8.0,kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CAST/EiJ, CBA/CaJ, CBA/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, LG/J, LP/J, MA/MyJ, MOL/Ei, NZB/BlNJ, PL/J, RF/J, SEC/1ReJ, SF/CamEiJ, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 10.0,8.0kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, I/LnJ, P/J, PRO/1ReJ, SJL/J
c 12.7,9.0,6.4kb CE/J, IS/Cam
d 10.0,9.0,3.6,2.1kb RIIIS/J
e 12.7,9.0,3.6kb SK/Cam
f 12.7,9.0,6.4,2.1kb PERA
MspI Saa1 a 2.3,1.9,0.5kb C57BL/10Sn
b 1.8,0.9,0.5kb B10.129-SelenosH47-b/(21M)Sn
c 0.5kb IS/Cam
PvuII Saa1 a 6.4,1.5,1.3kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CAST/EiJ, CBA/CaJ, CBA/J, CE/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, IS/Cam, LG/J, LP/J, MA/MyJ, NZB/BlNJ, PERA, PL/J, RF/J, RIIIS/J, SEC/1ReJ, SF/CamEiJ, SK/Cam, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 7.2,1.8,1.5kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, I/LnJ, MOLF/EiJ, P/J, PRO/1ReJ, SJL/J
SstI Saa1 a 8.0,4.7kb C57BL/10Sn
b,c 9.2,8.0,5.0kb B10.129-SelenosH47-b/(21M)Sn, IS/Cam
References
J:6644 Morrow JF, et al., Induction of hepatic synthesis of serum amyloid A protein and actin. Proc Natl Acad Sci U S A. 1981 Aug;78(8):4718-22
J:17551 Stearman RS, et al., Regulation of synthesis of amyloid A-related protein. Ann N Y Acad Sci. 1982;389:106-15
J:7560 Taylor BA, et al., Genes for serum amyloid A proteins map to Chromosome 7 in the mouse. Mol Gen Genet. 1984;195(3):491-9
J:8180 Stearman RS, et al., The sequence and structure of a new serum amyloid A gene. Nucleic Acids Res. 1986 Jan 24;14(2):797-809
J:9600 Rienhoff HY Jr, et al., Regulation of amyloid A gene expression in cultured cells. Mol Cell Biol. 1988 Sep;8(9):3710-6
J:10993 Saunders AM, et al., A molecular genetic linkage map of mouse chromosome 7. Genomics. 1990 Nov;8(3):525-35
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12/17/2024
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