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pIi-5 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pIi-5
  • Sequence Type
    cDNA
  • ID
    MGI:11914
  • Region Covered
    encodes most of the coding sequence and 3' untranslated region
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    1170bp
  • Note
    This clone encodes an alternatively spliced transcript (Ii31).
Source
  • Species
    mouse, laboratory
  • Tissue
    spleen
Genes
Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Polymorphisms
J:7977 Richards JE, et al., Immunogenetics. 1985;22(2):193-9
Endonuclease Gene Allele Fragments Strains
EcoRI Cd74 b 10.0kb C57BL/6J
c 12.5kb BALB/c
XbaI Cd74 a 10.0kb AKR/J
b 9.0,1.1kb C57L, DBA/2J
References
J:20103 Singer PA, et al., Structure of the murine Ia-associated invariant (Ii) chain as deduced from a cDNA clone. EMBO J. 1984 Apr;3(4):873-7
J:7977 Richards JE, et al., Murine invariant chain gene: chromosomal assignment and segregation in recombinant inbred strains. Immunogenetics. 1985;22(2):193-9
J:20082 Koch N, et al., Primary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin. EMBO J. 1987 Jun;6(6):1677-83
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory