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pMK174 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pMK174
  • Sequence Type
    cDNA
  • ID
    MGI:11961
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    1.0kb
Source
  • Species
    mouse, laboratory
  • Tissue
    kidney
Genes
D4Rp18 DNA segment, Chr 4, Roswell Park 18
Map3k4 mitogen-activated protein kinase kinase kinase 4
Polymorphisms
J:8357 Sarvetnick N, et al., Genetics. 1986 Jul;113(3):723-34
Notes: Strains and/or t haplotype designations appear in the allele groupings. Additionally pMK174 detects a poorly characterized polymorphism, also located on chromosome 17.
Endonuclease Gene Allele Fragments Strains
BamHI D4Rp18 a 1.7kb DBA/2J
b 14.6kb 129P3/J
BamHI Map3k4 a 5.4,1.6kb C3.t12, C3.tw5, STOCK tw32
b 4.1,2.8kb 129P3/J, DBA/2J, STOCK twLub2
J:8526 Mann EA, et al., Genetics. 1986 Nov;114(3):993-1006
Notes: The 6.3 and 6.1 kb fragments define the D17Rp17 locus.
Endonuclease Gene Allele Fragments Strains
BamHI D4Rp18 c 1.7kb C57BL/6J, DBA/2J, GRS/A
m 14.6kb 129P3/J, BDP/J, I/LnJ, LP/J, M. m. castaneus, M. m. molossinus, MOLD/RkA, SB/LeJ
BamHI Map3k4 b 6.3,4.1,2.8,1.7kb 129P3/J, ABP/LeJ, AKR/J, AU/SsJ, BALB/cByJ, BDP/J, BUB/BnJ, C57BL/6J, C57BL/10J, C57BL/Spr, C57L/J, C58/J, CE/J, DW/J, FS/EiJ, I/LnJ, LG/J, LP/J, MA/MyJ, NZB/BlNJ, O20/A, P/J, RF/J, RIIIS/J, SB/LeJ, SEC/1ReJ, SJL/J, ST/bJ, SWR/J, WB/ReJ
d 6.1,4.1,2.8,1.7kb A/J, C3H/HeJ, C3HeB/FeJ, C57BLKS/J, CBA/CaJ, DBA/1J, DBA/2J, PL/J, SM/J, YBR/Ki
J:9490 MacMurray A, et al., Genetics. 1988 Oct;120(2):545-50
Notes: t-haplotype designations appear in the allele groupings.
Endonuclease Gene Allele Fragments Strains
BamHI Map3k4 a 4.1,2.8kb C3H/DiSn, STOCK Tc
b 5.4,1.6kb C3.t0, C3.t12, STOCK t1
J:9547 King TR, et al., Proc Natl Acad Sci U S A. 1989 Jan;86(1):222-6
Endonuclease Gene Allele Fragments Strains
BamHI Map3k4 b 6.3kb BTBR
d 6.1kb A/J
J:10663 Eicher EM, et al., Genetics. 1990 Jun;125(2):431-46
Endonuclease Gene Allele Fragments Strains
BamHI Map3k4 n 6.4kb NZB
s 6.1kb SM
J:10943 Washburn LL, et al., Genet Res. 1990 Oct-Dec;56(2-3):185-91
Notes: Multiple fragments are detected with probe pMK174.
Endonuclease Gene Allele Fragments Strains
BamHI Map3k4 b 6.4kb C57BL/6J
d 6.1kb C3H/HeSnJ
J:27401 Miyazaki S, et al., Genomics. 1995 Jun 10;27(3):420-4
Endonuclease Gene Allele Fragments Strains
EcoRI Map3k4 c not given C58/J
m not given M. m. musculus
n not given NFS/N
s not given M. spretus
J:31802 Gregorova S, et al., Mamm Genome. 1996 Feb;7(2):107-13
Endonuclease Gene Allele Fragments Strains
BamHI Map3k4 b not given C57BL/10SnPh-T
c not given C3H/DiPh
References
J:8357 Sarvetnick N, et al., Nonhomologous pairing in mice heterozygous for a t haplotype can produce recombinant chromosomes with duplications and deletions. Genetics. 1986 Jul;113(3):723-34
J:8526 Mann EA, et al., Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone. Genetics. 1986 Nov;114(3):993-1006
J:9490 MacMurray A, et al., The antimorphic nature of the Tc allele at the mouse T locus. Genetics. 1988 Oct;120(2):545-50
J:9547 King TR, et al., Mapping to molecular resolution in the T to H-2 region of the mouse genome with a nested set of meiotic recombinants. Proc Natl Acad Sci U S A. 1989 Jan;86(1):222-6
J:10663 Eicher EM, et al., The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics. 1990 Jun;125(2):431-46
J:10943 Washburn LL, et al., Inheritance of T-associated sex reversal in mice. Genet Res. 1990 Oct-Dec;56(2-3):185-91
J:460 King TR, et al., Meiotic mapping of murine chromosome 17: the string of loci around l(17)-2Pas. Mamm Genome. 1991;1(1):37-46
J:27401 Miyazaki S, et al., The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics. 1995 Jun 10;27(3):420-4
J:31802 Gregorova S, et al., Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene. Mamm Genome. 1996 Feb;7(2):107-13
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