pH-2IIa Probe Detail MGI Mouse MGI:12067

pH-2IIa Probe Detail

Name

pH-2IIa
Sequence Type

cDNA
ID

MGI:12067
Region Covered

encodes a 3' portion of the coding region and 3'-untranslated region
Parent Clone

pH-2II
Vector Type

Plasmid
Insert Size

~680bp
Synonyms

pH2IIa

Species

mouse, laboratory
Strain

BALB/c
Tissue

lymphocyte
Cell Line

lymphoma cell line C14

H2	histocompatibility-2, MHC
H2-D1	histocompatibility 2, D region locus 1
H2-Q	histocompatibility 2, Q region
H2-Q1	histocompatibility 2, Q region locus 1
H2-Q11	histocompatibility 2, Q region locus 11
H2-Q4	histocompatibility 2, Q region locus 4
H2-Q5	histocompatibility 2, Q region locus 5
H2-T	histocompatibility 2, T region
H2-Q15	histocompatibility 2, Q region locus 15
H2-Q14	histocompatibility 2, Q region locus 14
H2-Q13	histocompatibility 2, Q region locus 13
H2-Q12	histocompatibility 2, Q region locus 12

J:11962 Steinmetz M, et al., Cell. 1981 Sep;25(3):683-92

Notes: Numerous common bands are also displayed.

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	H2	d	2.7kb	BALB/c
BamHI	H2	k	absent	CBA

J:6934 Shin HS, et al., Cell. 1982 Jul;29(3):969-76

Notes: A 1.3 kb fragment encoding the 5' portion of pH-2IIa and some pBR322 sequence was isolated and used in Southern analysis. Strains and/or t haplotype designations appear in the allele groupings.

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	H2	a	multiple	BALB/c
		b	multiple	AKR, C3H/DiSn, C57BL/6-H2^k
		c	multiple	C3.t¹²/t¹, C3.t^w12/t^w32, C3H-t^w2
		d	multiple	B6.Cg-H2^b3/FlaCmwJ
		e	multiple	B6.TL
		f	multiple	A/J
		g	multiple	SM/J
		h	multiple	SWR/J
EcoRI	H2	a	multiple	BALB/c
		b	multiple	AKR, C3H/DiSn, C57BL/6-H2^k
		c	multiple	C3.t¹²/t¹, C3.t^w12/t^w32, C3H-t^w2
		d	multiple	B6.Cg-H2^b3/FlaCmwJ
		e	multiple	B6.TL
		f	multiple	A/J
		g	multiple	SM/J
		h	multiple	SWR/J

J:7763 Flaherty L, et al., Proc Natl Acad Sci U S A. 1985 Mar;82(5):1503-7

Endonuclease	Gene	Allele	Fragments	Strains
XbaI	H2-Q	a	multiple	B6.Cg-H2^b3/FlaCmwJ
XbaI	H2-Q	b	multiple	B6.Cg-H2^b4/FlaCmwJ
XbaI	H2-Q	a	3.7kb	A, A H2-T18^a, B6.Cg-H2^b4/FlaCmwJ, BALB/c-PC1, BALB/cAr, BALB/cFla, BALB/cJ, BALB/cOrnl, BALB/cWt, C57BL/6-H2-T18^a, C57BL/6Fla, C57BL/6J, CAST/EiJ, DBA/2, MOLI/Ei
XbaI	H2-Q	b	absent	A.CA-H2^f/Sn, B6.AK1, B6.Cg-H2^b3/FlaCmwJ, BALB/cBy, BALB/cByKh, BALB/cKh-H2^dm2, C3H/HeJ, C57BL/6-H2^k, P/J
XbaI	H2-T	a	multiple	C57BL/6
XbaI	H2-T	b	multiple	C57BL/6-H2-T18^a

J:8689 Kotzin BL, et al., J Exp Med. 1987 May 1;165(5):1237-51

Endonuclease	Gene	Allele	Fragments	Strains
PvuII	H2	d	-	NZB
PvuII	H2	z	4.1,1.8kb	NZW

J:10105 Richards S, et al., EMBO J. 1989 Dec 1;8(12):3749-57

Endonuclease	Gene	Allele	Fragments	Strains
BglII	H2	c	not given	C3H/HeJ
BglII	H2	r	17.0kb	R4
EcoRI	H2	c	5.0kb	C3H/HeJ
EcoRI	H2	r	7.0kb	R4
HindIII	H2	c	not given	C3H/HeJ
HindIII	H2	r	not given	R4
KpnI	H2	c	not given	C3H/HeJ
KpnI	H2	r	6.0kb	R4
PstI	H2	c	9.0kb	C3H/HeJ
PstI	H2	r	7.0kb	R4

J:11962 Steinmetz M, et al., A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell. 1981 Sep;25(3):683-92

J:6934 Shin HS, et al., Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes. Cell. 1982 Jul;29(3):969-76

J:7763 Flaherty L, et al., Characterization of a Q subregion gene in the murine major histocompatibility complex. Proc Natl Acad Sci U S A. 1985 Mar;82(5):1503-7

J:8689 Kotzin BL, et al., The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice. J Exp Med. 1987 May 1;165(5):1237-51

J:8713 Uehara H, et al., The molecular organization of the H-2K region of two t-haplotypes: implications for the evolution of genetic diversity. EMBO J. 1987 Jan;6(1):83-90

J:10105 Richards S, et al., Genetic and molecular mapping of the Hmt region of mouse. EMBO J. 1989 Dec 1;8(12):3749-57

J:13181 Wang CR, et al., Organization and structure of the H-2M4-M8 class I genes in the mouse major histocompatibility complex. Immunogenetics. 1993;38(4):258-71

J:32012 Litaker W, et al., A physical map of the Q region of B1O.P. Mamm Genome. 1996 Mar;7(3):200-5

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