pAB-lambda-I-1
Probe Detail
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Name
pAB-lambda-I-1
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Sequence Type
cDNA
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ID
MGI:12160
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Region Covered
encodes gene segment Igl-V1, Igl-J1 and Igl-C1
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Child Clones
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Vector Type
Plasmid
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Insert Site
PstI
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Insert Size
~550 bp
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Note
This probe may hybridize to both the Igl-C1 and Igl-C4 gene segments.
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Synonyms
pAB-lambda-1,
pAB-lambda-1-1
|
Iglv1
|
immunoglobulin lambda variable 1
|
|
|
Igl-J
|
immunoglobulin lambda chain, joining region
|
|
|
Iglc1
|
immunoglobulin lambda constant 1
|
|
|
Iglv2
|
immunoglobulin lambda variable 2
|
|
J:20081
Kindt TJ, et al., Eur J Immunol. 1985 Jun;15(6):535-40
Notes: An XbaI fragment encoding a portion of gene segment Igl-C1 was isolated and used in Southern analysis. The 9.2 kb HindIII BALB/c fragment contains the Igl-C1 gene segment while the 3.6 kb contains the Igl-C4.
| Endonuclease |
Gene |
Allele |
Fragments |
Strains |
| EcoRI |
Iglc1 |
b |
8.0kb |
BALB/c, SJL |
| s |
6.7kb |
SPE |
| HindIII |
Iglc1 |
b |
9.2,3.6kb |
BALB/c |
| m |
~15,~8.0,3.6kb |
MOL |
| s |
~3.9,~4.1kb |
SPE |
J:6539
D'Eustachio P, et al., Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains. J Exp Med. 1981 Apr 1;153(4):793-800
J:20008
Bothwell AL, et al., Dual expression of lambda genes in the MOPC-315 plasmacytoma. Nature. 1981 Mar 5;290(5801):65-7
J:20081
Kindt TJ, et al., Lambda light chain constant and variable gene complements in wild-derived inbred mouse strains. Eur J Immunol. 1985 Jun;15(6):535-40
J:8234
Epstein R, et al., Position of Igl-1, md, and Bst loci on chromosome 16 of the mouse. Immunogenetics. 1986;23(2):78-83
Analysis Tools