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Id-2 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Id-2
  • Sequence Type
    cDNA
  • ID
    MGI:12226
  • Region Covered
    full length
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    1.4 kb
  • Note
    Hybridizes to Ren-1 and Ren-2.
  • Synonyms
    pDD-1D2
Source
  • Species
    mouse, laboratory
  • Strain
    DBA/2J
  • Tissue
    submaxillary salivary gland
Genes
Ren1 renin 1 structural
Ren2 renin 2 tandem duplication of Ren1
Polymorphisms
J:9230 Seldin MF, et al., Genomics. 1988 Jan;2(1):48-56
Notes: Fragment sizes are estimated from gels. "1" or "2" refer to the presence of one or two renin genes.
Endonuclease Gene Allele Fragments Strains
EcoRI Ren1 1 8.0,4.0kb A/He, A/J, ABP/LeJ, BALB/c, C3H/HeJ, C3H/HeN, C57BL/6J, C57BL/10J, C57BR/cdJ, C57L/J, C58/J, CBA/N, CE/J, HRS/J, SEA/GnJ, SEC/1ReJ
2 8.0,4.3,4.0kb 129P3/J, AKR/J, AL/N, BDP/J, BSVS, BUB/BnJ, C3H/Fg, CBA/J, DBA/1J, DBA/2J, DD, I/LnJ, MA/MyJ, MRL/MpJ, NFS, NH, NZB/N, O20, RF/J, RIIIS/J, SJL/J, SJL/JLwPt, SM/J, ST/bJ, STS/A, STS/J, SWR/J, YBR/EiJ
EcoRI Ren2 1 8.0,4.0kb A/He, A/J, ABP/LeJ, BALB/c, C3H/HeJ, C3H/HeN, C57BL/6J, C57BL/10J, C57BR/cdJ, C57L/J, C58/J, CBA/N, CE/J, HRS/J, SEA/GnJ, SEC/1ReJ
2 8.0,4.3,4.0kb 129P3/J, AKR/J, AL/N, BDP/J, BSVS, BUB/BnJ, C3H/Fg, CBA/J, DBA/1J, DBA/2J, DD, I/LnJ, MA/MyJ, MRL/MpJ, NFS, NH, NZB/N, O20, RF/J, RIIIS/J, SJL/J, SM/J, ST/bJ, STS/A, STS/J, SWR/J, YBR/EiJ
J:9342 Seldin MF, et al., Curr Top Microbiol Immunol. 1988;137:227-32
Endonuclease Gene Allele Fragments Strains
Not Specified Ren1 c not given C3H/HeJ-Faslgld/J
s not given M. spretus
Not Specified Ren2 c not given C3H/HeJ-Faslgld/J
s not given M. spretus
J:10189 Barnum SR, et al., Biochemistry. 1989 Oct 17;28(21):8312-7
Notes: A 1.4 kb PstI fragment was used for Southern analysis. Only diagnostic fragments are listed.
Endonuclease Gene Allele Fragments Strains
BamHI Ren2 c absent C3H-Faslgld
s ~9.0,6.6kb M. spretus
J:10476 Mock B, et al., Genomics. 1990 May;7(1):57-64
Notes: A 1.4kb PstI portion of the clone was used for Southern blotting.
Endonuclease Gene Allele Fragments Strains
EcoRI Ren1 c absent BALB/c
d 4.3kb DBA/2
EcoRI Ren2 c absent BALB/c
d 4.3kb DBA/2
J:11044 Copeland NG, et al., Genomics. 1991 Jan;9(1):44-50
Endonuclease Gene Allele Fragments Strains
BamHI Ren2 b 10.4,5.8kb C57BL/6J
s 10.4,7.1kb M. spretus
J:15235 Mock BA, et al., Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9499-503
Endonuclease Gene Allele Fragments Strains
EcoRI Ren1 c not given BALB/c
d 4.3kb DBA/2N
References
J:7511 Field LJ, et al., Tissue and gene specificity of mouse renin expression. Hypertension. 1984 Jul-Aug;6(4):597-603
J:9130 Abel KJ, et al., Close physical linkage of the murine Ren-1 and Ren-2 loci. Nucleic Acids Res. 1988 Mar 25;16(5):2111-26
J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
J:9342 Seldin MF, et al., A molecular genetic approach to gld autoimmune disease. Curr Top Microbiol Immunol. 1988;137:227-32
J:10189 Barnum SR, et al., Molecular analysis of the murine C4b-binding protein gene. Chromosome assignment and partial gene organization. Biochemistry. 1989 Oct 17;28(21):8312-7
J:10476 Mock B, et al., A genetic map of mouse chromosome 1 near the Lsh-Ity-Bcg disease resistance locus. Genomics. 1990 May;7(1):57-64
J:11044 Copeland NG, et al., Chromosomal location of murine and human IL-1 receptor genes. Genomics. 1991 Jan;9(1):44-50
J:15235 Mock BA, et al., Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9499-503
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