probe 7 Probe Detail MGI Mouse MGI:12293

probe 7 Probe Detail

Name

probe 7
Sequence Type

genomic
ID

MGI:12293
Region Covered

encodes the H-2Ea exons 2-4
Parent Clone

cosmid 32.1
Vector Type

Plasmid
Insert Site

SalI
Insert Size

3.4 kb

Species

mouse, laboratory
Strain

BALB/c
Tissue

sperm

H2-Ea

histocompatibility 2, class II antigen E alpha

J:6885 Steinmetz M, et al., Nature. 1982 Nov 4;300(5887):35-42

Endonuclease	Gene	Allele	Fragments	Strains
EcoRI	H2-Ea	b	8.6,3kb	B10.A-H2ⁱ³/(3R), C3H
EcoRI	H2-Ea	c	8.2,3kb	A.SW-H2^s/Sn, B10.M-H2^ap1/(11R), B10.Q-H2^q/SgJ, BALB/c, C57BL/6
HpaI	H2-Ea	b	18,4.4kb	B10.A-H2ⁱ³/(3R), C3H
HpaI	H2-Ea	c	9.8,4.4kb	A.SW-H2^s/Sn, BALB/c, C57BL/6

J:7253 Shin HS, et al., Nature. 1983 Nov 24-30;306(5941):380-3

Notes: Strains and/or t haplotype designations appear in the allele groupings.

Endonuclease	Gene	Allele	Fragments	Strains
HindIII	H2-Ea	a	9.0kb	C3.t^w12, STOCK t^K115, STOCK t^K120, STOCK t^K130, STOCK t^S510, STOCK t^S735
		b	8.1kb	STOCK t^K100, STOCK t^w32
		c	8.4kb	C3H

J:7675 Shin HS, et al., Cell. 1984 Dec;39(3 Pt 2):573-8

Notes: Strain and/or t haplotype designations appear in the allele groupings.

Endonuclease	Gene	Allele	Fragments	Strains
HindIII	H2-Ea	a	9.0kb	C3H-T/t^w12
HindIII	H2-Ea	b	8.1kb	C3.t¹², STOCK t^w32
PstI	H2-Ea	a	2.7kb	C3.t¹², STOCK t^w32
PstI	H2-Ea	b	3.0kb	C3.t^w5

J:15532 Steinmetz M, et al., EMBO J. 1984 Dec 1;3(12):2995-3003

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	H2-Ea	a	6.6kb	A.SW-H2^s/Sn, B10.DRB62, B10.KPA44, B10.STA10, B10.STA62, BALB/c, C3H, C57BL/6
BamHI	H2-Ea	b	6.6,5.8kb	B10.CAS2
EcoRI	H2-Ea	a	8.2,3.0kb	A.SW-H2^s/Sn, B10.DRB62, B10.KPA44, B10.STA62, BALB/c, C57BL/6
		b	8.6,3.0kb	C3H
		c	7.5,3.0kb	B10.STA10
		d	7.8,3.0kb	B10.CAS2
HindIII	H2-Ea	a	9.0kb	A.SW-H2^s/Sn, B10.KPA44, B10.STA10, B10.STA62, BALB/c, C3H, C57BL/6
		b	8.0kb	B10.CAS2
		c	8.6kb	B10.DRB62
KpnI	H2-Ea	a	8.8,4.2kb	B10.DRB62, B10.KPA44, B10.STA10, B10.STA62, BALB/c, C3H
KpnI	H2-Ea	b	8.8,3.5kb	A.SW-H2^s/Sn, B10.CAS2, C57BL/6

J:8530 Lafuse WP, et al., Immunogenetics. 1986;24(6):352-60

Endonuclease	Gene	Allele	Fragments	Strains
DraI	H2-Ea	a	7.2kb	B10.K-H2^k, B10.RSB5, B10.RSB6, B10.RSB8, B10.RSB11, B10.RSB12, B10.RSB14, B10.RSB15, B10.S-H2^t4/(9R)/J, B10.TL-H2^r1
DraI	H2-Ea	b	4.4kb	B10.F-H2^pb1/(13R)J, B10.P-H2^p, B10.RPD1, B10.RPD2
PstI	H2-Ea	a	6.2,2.7kb	B10.F-H2^pb1/(13R)J, B10.P-H2^p
		b	6.2,3.3kb	B10.RSB6, B10.RSB8, B10.RSB11, B10.RSB12, B10.RSB15
		c	5.8,3.3kb	B10.K-H2^k, B10.RSB5, B10.RSB14, B10.S-H2^t4/(9R)/J, B10.TL-H2^r1
		d	5.8,2.7kb	B10.RPD1, B10.RPD2

J:20297 Lafuse WP, et al., J Exp Med. 1986 Jun 1;163(6):1518-28

Endonuclease	Gene	Allele	Fragments	Strains
HapI	H2-Ea	a	18,4.4kb	B10.K-H2^k, B10.RSB5, B10.RSB6, B10.RSB8, B10.RSB11, B10.RSB12, B10.RSB14, B10.RSB15, B10.S-H2^t4/(9R)/J, B10.TL-H2^r1
HapI	H2-Ea	b	9.8,4.4kb	B10.F-H2^pb1/(13R)J, B10.P-H2^p
HpaI	H2-Ea	a	18,4.4kb	B10.K-H2^k
HpaI	H2-Ea	b	9.8,4.4kb	B10.P-H2^p, B10.RPD1, B10.RPD2
RsaI	H2-Ea	a	2.0,1.7,1.0kb	B10.K-H2^k, B10.RPD1, B10.RPD2, B10.RSB5, B10.RSB14, B10.S-H2^t4/(9R)/J, B10.TL-H2^r1
RsaI	H2-Ea	b	2.8,1.7,1.0kb	B10.F-H2^pb1/(13R)J, B10.P-H2^p, B10.RSB6, B10.RSB8, B10.RSB11, B10.RSB12, B10.RSB15, B10.S-H2^t4/(9R)/J, B10.TL-H2^r1
SacI	H2-Ea	a	20,1.7kb	B10.K-H2^k
SacI	H2-Ea	b	15,1.7kb	B10.P-H2^p, B10.RPD1, B10.RPD2
SacI	H2-Ea	a	~20,~1.7kb	B10.K-H2^k, B10.RSB5, B10.RSB6, B10.RSB8, B10.RSB11, B10.RSB12, B10.RSB14, B10.RSB15, B10.S-H2^t4/(9R)/J, B10.TL-H2^r1
SacI	H2-Ea	b	~15,~1.7kb	B10.F-H2^pb1/(13R)J, B10.P-H2^p

J:6885 Steinmetz M, et al., A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature. 1982 Nov 4;300(5887):35-42

J:20091 McNicholas J, et al., DNA sequence of the gene encoding the E alpha Ia polypeptide of the BALB/c mouse. Science. 1982 Dec 17;218(4578):1229-32

J:7253 Shin HS, et al., Inversion in the H-2 complex of t-haplotypes in mice. Nature. 1983 Nov 24-30;306(5941):380-3

J:7675 Shin HS, et al., Gene mapping within the T/t complex of the mouse. IV: The inverted MHC is intermingled with several t-lethal genes. Cell. 1984 Dec;39(3 Pt 2):573-8

J:15532 Steinmetz M, et al., Tracts of high or low sequence divergence in the mouse major histocompatibility complex. EMBO J. 1984 Dec 1;3(12):2995-3003

J:8530 Lafuse WP, et al., Recombination hot spots within the I region of the mouse H-2 complex map to the E beta and E alpha genes. Immunogenetics. 1986;24(6):352-60

J:20297 Lafuse WP, et al., Mapping of a second recombination hot spot within the I-E region of the mouse H-2 gene complex. J Exp Med. 1986 Jun 1;163(6):1518-28

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