Rrm2 cDNA Probe Detail MGI Mouse MGI:12401

Rrm2 cDNA Probe Detail

Name

Rrm2 cDNA
Sequence Type

cDNA
ID

MGI:12401
Region Covered

full length cDNA
Vector Type

Plasmid
Insert Site

PstI
Insert Size

~2.1 kb
Note

Clone 10 and Rrm2 cDNA are similar probes. Rrm2 cDNA is also referred to as Clone 22 and will hybridize with Rrm2-ps1, Rrm2-ps2, and Rrm2-ps3. Subcloned into pUC18.
Synonyms

Clone 22

Species

mouse, laboratory
Tissue

mammary gland
Cell Line

tumor cell line TA3

Rrm2	ribonucleotide reductase M2
Rrm2-ps1	ribonucleotide reductase M2 pseudogene 1
Rrm2-ps2	ribonucleotide reductase M2 pseudogene 2
Rrm2-ps3	ribonucleotide reductase M2 pseudogene 3

M14223 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)

J:10133 Ceci JD, et al., Genomics. 1989 Nov;5(4):699-709

Notes: The RFLV fragments of 15, 2.1, and 1.2 kb in M.spretus have been mapped to chromosomes 7, 12 and 13 respectively.

Endonuclease	Gene	Allele	Fragments	Strains
TaqI	Rrm2-ps1	b	4.6,2.8,2.5,2.3,1.7,1.0,0.8,0.7,0.6,0.5kb	C57BL/6J
TaqI	Rrm2-ps1	s	15,3.1,2.8,2.5,2.1,1.9,1.2,1.0,0.7,0.6,0.5kb	M. spretus

J:10344 Justice MJ, et al., Genomics. 1990 Feb;6(2):341-51

Endonuclease	Gene	Allele	Fragments	Strains
TaqI	Rrm2-ps3	b	4.6,2.8,2.5,2.3,1.7,1.0,0.8,0.7,0.6,0.5kb	C57BL/6J
TaqI	Rrm2-ps3	s	15.5,3.1,2.8,2.5,2.1,1.9,1.2,1.0,0.7,0.6,0.5kb	M. spretus

J:8537 Thelander L, et al., Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase. Mol Cell Biol. 1986 Oct;6(10):3433-42

J:8879 Yang-Feng TL, et al., Ribonucleotide reductase M2 subunit sequences mapped to four different chromosomal sites in humans and mice: functional locus identified by its amplification in hydroxyurea-resistant cell lines. Genomics. 1987 Sep;1(1):77-86

J:10133 Ceci JD, et al., A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes. Genomics. 1989 Nov;5(4):699-709

J:10344 Justice MJ, et al., A molecular genetic linkage map of mouse chromosome 13 anchored by the beige (bg) and satin (sa) loci. Genomics. 1990 Feb;6(2):341-51

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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