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clone II5.22 Probe Detail
Nucleotide
Probe/Clone
  • Name
    clone II5.22
  • Sequence Type
    genomic
  • ID
    MGI:12735
  • Region Covered
    Encodes centromeric flank sequence, H2-Ma (5 exons), H2-Mb2 (6 exons), H2-Mb1 (6 exons) and their associated intergenic regions. The flanking sequence centromeric to H2-Ma contains the 4.24A expressed sequence and the 4.24F sequence.
  • Child Clone
  • Vector Type
    Cosmid
  • Insert Size
    ~39.0kb
  • Synonyms
    clone 5.22
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    liver
Genes
H2-Ob histocompatibility 2, O region beta locus
H2-Pb histocompatibility 2, P region beta locus
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
H2-DMa histocompatibility 2, class II, locus DMa
H2-DMb1 histocompatibility 2, class II, locus Mb1
H2-DMb2 histocompatibility 2, class II, locus Mb2
Ms10s minisatellite 10s detected by probe MMS10
Sequences
References
J:8224 Steinmetz M, et al., Gene organization and recombinational hotspots in the murine major histocompatibility complex. Cell. 1986 Mar 28;44(6):895-904
J:11259 Cho S, et al., A cluster of transcribed sequences between the Pb and Ob genes of the murine major histocompatibility complex. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5197-201
J:31628 Peleraux A, et al., Genomic organization of a mouse MHC class II region including the H2-M and Lmp2 loci. Immunogenetics. 1996;43(4):204-14

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory