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Gli cDNA3 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Gli cDNA3
  • Sequence Type
    cDNA
  • ID
    MGI:1277646
  • Region Covered
    includes a region outside the zinc-finger domain
  • Insert Size
    0.26 kb
  • Synonyms
    pGli
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 11.5
Genes
Gli1 GLI-Kruppel family member GLI1
Expression
  • Assay Results
    311
References
J:12857 Walterhouse D, et al., gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development. Dev Dyn. 1993 Feb;196(2):91-102
J:17485 Hui CC, et al., Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13
J:35809 Epstein DJ, et al., Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development. 1996 Sep;122(9):2885-94
J:38381 Mo R, et al., Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development. 1997 Jan;124(1):113-23
J:39659 Platt KA, et al., Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice. Mech Dev. 1997 Mar;62(2):121-35
J:40587 Persengiev SP, et al., Gli family members are differentially expressed during the mitotic phase of spermatogenesis. Oncogene. 1997 May 15;14(19):2259-64
J:41684 Lee J, et al., Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development. 1997 Jul;124(13):2537-52
J:49164 Ding Q, et al., Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43
J:49251 Matise MP, et al., Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development. 1998 Aug;125(15):2759-70
J:50462 Dassule HR, et al., Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15;202(2):215-27
J:49322 Zuniga A, et al., Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity. Development. 1999 Jan;126(1):13-21
J:52207 Chiang C, et al., Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol. 1999 Jan 1;205(1):1-9
J:53903 Theil T, et al., Gli3 is required for Emx gene expression during dorsal telencephalon development. Development. 1999 Aug;126(16):3561-71
J:56424 Goodrich LV, et al., Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube. Dev Biol. 1999 Jul 15;211(2):323-34
J:57297 St-Jacques B, et al., Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation [published erratum appears in Genes Dev 1999 Oct 1;13(19):2617]. Genes Dev. 1999 Aug 15;13(16):2072-86
J:59288 Baur ST, et al., Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development. 2000 Feb;127(3):605-19
J:59923 Tole S, et al., Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol. 2000 Jan 15;217(2):254-65
J:64180 Outram SV, et al., Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity. 2000 Aug;13(2):187-97
J:72303 Haraguchi R, et al., Unique functions of Sonic hedgehog signaling during external genitalia development. Development. 2001 Nov;128(21):4241-50
J:73074 Bai CB, et al., Gli1 can rescue the in vivo function of Gli2. Development. 2001 Dec;128(24):5161-72
J:73075 Dahmane N, et al., The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development. 2001 Dec;128(24):5201-12
J:79856 Rallu M, et al., Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development. 2002 Nov;129(21):4963-74
J:88955 Schwabe GC, et al., Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn. 2004 Feb;229(2):400-10
J:104488 Ozaki H, et al., Six1 controls patterning of the mouse otic vesicle. Development. 2004 Feb;131(3):551-62
J:101265 Kuijper S, et al., Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh. Dev Biol. 2005 Sep 15;285(2):533-44
J:104154 Rice R, et al., Expression patterns of Hedgehog signalling pathway members during mouse palate development. Gene Expr Patterns. 2006 Jan;6(2):206-12
J:110617 Stottmann RW, et al., The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol. 2006 Jul 15;295(2):647-63
J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
J:119913 Haraguchi R, et al., Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling. Development. 2007 Feb;134(3):525-33
J:259785 Evangelista M, et al., Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction. Sci Signal. 2008 Sep 30;1(39):ra7
J:150375 Cobourne MT, et al., Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49
J:153731 Pazin DE, et al., Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov;238(11):2877-90
J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
J:160585 Kesper DA, et al., Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26
J:170258 Mavromatakis YE, et al., Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity. Mech Dev. 2011 Jan-Feb;128(1-2):90-103
J:264204 Deimling SJ, et al., Genetic interaction between Gli3 and Ezh2 during limb pattern formation. Mech Dev. 2018 Jun;151:30-36
J:292270 Ideno H, et al., G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332
J:302594 Hall ET, et al., Cytoneme delivery of sonic hedgehog from ligand-producing cells requires Myosin 10 and a dispatched-BOC/CDON co-receptor complex. Elife. 2021 Feb 11;10:e61432
J:306168 Haraguchi R, et al., New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development. Int J Mol Sci. 2021 Jan 26;22(3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory