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p3'-alpha Probe Detail
Nucleotide
Probe/Clone
  • Name
    p3'-alpha
  • Sequence Type
    genomic
  • ID
    MGI:12825
  • Region Covered
    encodes genomic sequence 3-4 kb 3' to Igh-2 constant region gene segment
  • Vector Type
    Plasmid
  • Insert Site
    BamHI/BglII
  • Insert Size
    1.3 kb
Source
  • Species
    mouse, laboratory
  • Strain
    I/St
Genes
Igha immunoglobulin heavy constant alpha
Igh-C immunoglobulin heavy chain constant region
Polymorphisms
J:9617 Blank RD, et al., Genetics. 1988 Dec;120(4):1073-83
Endonuclease Gene Allele Fragments Strains
TaqI Igh-C a 14,3.5,2.8kb BALB/cJ, STS/A
b 18,5.6kb C57BL/6J, O20/A, SJL/J
c 14,4.9kb AKR/J
d 14,3.7,2.9kb C57L/J
e 18,9.4kb SWR/J
f 18,14kb DBA/2J
g 5.4,3.1kb C3H/HeJ
J:9863 Brueckner M, et al., Proc Natl Acad Sci U S A. 1989 Jul;86(13):5035-8
Endonuclease Gene Allele Fragments Strains
BamHI Igha a 1.0,1.5,2.2,5.0kb (SI/Col x M. spretus)F1 x SI/Col or SI/Col x M. m. musculus)F1 x SI/Col
b 1.0,3.0,3.5,5.0kb C57BL/6J, SJL
J:455 Cho M, et al., Mamm Genome. 1991;1(1):30-6
Endonuclease Gene Allele Fragments Strains
TaqI Igh-C b ~5.0kb C57BL/6J
w ~9.0kb SWR/J
J:18817 Khan F, et al., Genomics. 1994 May 1;21(1):128-37
Endonuclease Gene Allele Fragments Strains
TaqI Igh-C b 5.6kb SJL/J
e 9.4kb SWR/J
References
J:8641 Brown EH, et al., Rate of replication of the murine immunoglobulin heavy-chain locus: evidence that the region is part of a single replicon. Mol Cell Biol. 1987 Jan;7(1):450-7
J:9617 Blank RD, et al., A linkage map of mouse chromosome 12: localization of Igh and effects of sex and interference on recombination. Genetics. 1988 Dec;120(4):1073-83
J:9863 Brueckner M, et al., Linkage mapping of a mouse gene, iv, that controls left-right asymmetry of the heart and viscera. Proc Natl Acad Sci U S A. 1989 Jul;86(13):5035-8
J:455 Cho M, et al., A linkage map of distal mouse chromosome 12. Mamm Genome. 1991;1(1):30-6
J:18817 Khan F, et al., Refinement of the DNA marker maps of mouse chromosome 12. Genomics. 1994 May 1;21(1):128-37
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory