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Nkx-2.5 probe Probe Detail
Nucleotide
Probe/Clone
  • Name
    Nkx-2.5 probe
  • Sequence Type
    cDNA
  • ID
    MGI:1303179
  • Region Covered
    nucleotides 820-1593; includes a portion of the coding region and the 3' untranslated region
  • Parent Clone
  • Vector Type
    Plasmid
  • Insert Size
    0.77kb
Source
  • Species
    mouse, laboratory
  • Tissue
    heart
Genes
Nkx2-5 NK2 homeobox 5
Expression
  • Assay Results
    33
References
J:15282 Lints TJ, et al., Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants [published erratum appears in Development 1993 Nov;119(3):969]. Development. 1993 Oct;119(2):419-31
J:46377 Biben C, et al., Murine cerberus homologue mCer-1: a candidate anterior patterning molecule. Dev Biol. 1998 Feb 15;194(2):135-51
J:50308 Searcy RD, et al., A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice. Development. 1998 Nov;125(22):4461-70
J:53293 Chang H, et al., Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999 Apr;126(8):1631-42
J:54909 Xavier-Neto J, et al., A retinoic acid-inducible transgenic marker of sino-atrial development in the mouse heart. Development. 1999 Jun;126(12):2677-87
J:54910 Clark TG, et al., The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart. Development. 1999 Jun;126(12):2631-42
J:63131 Liberatore CM, et al., Ventricular expression of tbx5 inhibits normal heart chamber development. Dev Biol. 2000 Jul 1;223(1):169-80
J:67751 Campione M, et al., Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice. Dev Biol. 2001 Mar 1;231(1):252-64
J:69468 Briegel KJ, et al., Identification and characterization of Lbh, a novel conserved nuclear protein expressed during early limb and heart development. Dev Biol. 2001 May 15;233(2):291-304
J:80726 Biben C, et al., NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis. Int J Dev Biol. 2002;46(4):415-22
J:81324 Smart N, et al., A differential screen for putative targets of the bHLH transcription factor Hand1 in cardiac morphogenesis. Mech Dev. 2002 Dec;119 Suppl 1:S65-71
J:90275 Lincoln J, et al., Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev Dyn. 2004 Jun;230(2):239-50
J:101738 Briegel KJ, et al., Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh. Development. 2005 Jul;132(14):3305-16

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory