About   Help   FAQ
cosmid 17.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    cosmid 17.1
  • Sequence Type
    genomic
  • ID
    MGI:13062
  • Region Covered
    encodes H-2K, intergenic sequence, H-2K2 and flank sequence
  • Child Clone
  • Vector Type
    Cosmid
  • Insert Site
    BglII
  • Insert Size
    ~40 kb
  • Synonyms
    C17.1
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Sex
    Male
  • Tissue
    sperm
Genes
H2-K1 histocompatibility 2, K1, K region
H2-K2 histocompatibility 2, K region locus 2
Polymorphisms
J:7080 Winoto A, et al., Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9
Notes: A 2.6 kb XhoI/NruI fragment derived from cosmid 17.1 was subcloned into the HincII site of M13mp8 and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
HindIII H2-K2 a 10.6kb AKR, B10.A-H2h1/(1R), B10.BDR1-H2g4, BALB/c, C3H
b 5.6kb B10.A-H2i3/(3R), C57BL/6
c absent A.AL-H2a1, A.BY-H2bc H2-T18f/SnJ, A.TL-H2t1, A/WySnJ, AQR, B6.Cg-H2b3/FlaCmwJ, B6.Cg-H2b4/FlaCmwJ, B10.A-H2a, B10.AKM-H2m/SnJ, B10.D2-H2d, B10.Q-H2q/SgJ, C57BL/6-H2-T18a, C57BL/6-H2k, C57BL/10
References
J:6906 Goodenow RS, et al., Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature. 1982 Nov 18;300(5889):231-7
J:20104 Steinmetz M, et al., Clusters of genes encoding mouse transplantation antigens. Cell. 1982 Mar;28(3):489-98
J:7080 Winoto A, et al., Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex. Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9
J:12798 Pease LR, et al., Unusual mutation clusters provide insight into class I gene conversion mechanisms. Mol Cell Biol. 1993 Jul;13(7):4374-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory