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cosmid 17.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    cosmid 17.1
  • Sequence Type
    genomic
  • ID
    MGI:13062
  • Region Covered
    encodes H-2K, intergenic sequence, H-2K2 and flank sequence
  • Child Clone
  • Vector Type
    Cosmid
  • Insert Site
    BglII
  • Insert Size
    ~40 kb
  • Synonyms
    C17.1
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Sex
    Male
  • Tissue
    sperm
Genes
H2-K1 histocompatibility 2, K1, K region
H2-K2 histocompatibility 2, K region locus 2
Polymorphisms
J:7080 Winoto A, et al., Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9
Notes: A 2.6 kb XhoI/NruI fragment derived from cosmid 17.1 was subcloned into the HincII site of M13mp8 and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
HindIII H2-K2 a 10.6kb AKR, B10.A-H2h1/(1R), B10.BDR1-H2g4, BALB/c, C3H
b 5.6kb B10.A-H2i3/(3R), C57BL/6
c absent A.AL-H2a1, A.BY-H2bc H2-T18f/SnJ, A.TL-H2t1, A/WySnJ, AQR, B6.K1, B6.K2, B10.A-H2a, B10.AKM-H2m/SnJ, B10.D2-H2d, B10.Q-H2q/SgJ, C57BL/6-H2-T18a, C57BL/6-H2k, C57BL/10
References
J:6906 Goodenow RS, et al., Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature. 1982 Nov 18;300(5889):231-7
J:20104 Steinmetz M, et al., Clusters of genes encoding mouse transplantation antigens. Cell. 1982 Mar;28(3):489-98
J:7080 Winoto A, et al., Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex. Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9
J:12798 Pease LR, et al., Unusual mutation clusters provide insight into class I gene conversion mechanisms. Mol Cell Biol. 1993 Jul;13(7):4374-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory