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cosmid 49.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    cosmid 49.1
  • Sequence Type
    genomic
  • ID
    MGI:13064
  • Region Covered
    encodes part of H-2T6, H-2T5 intergenic sequence H-2T4 and H-2T3
  • Vector Type
    Cosmid
  • Insert Site
    BglII
  • Insert Size
    ~37.0kb
  • Synonyms
    c49.1
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Sex
    Male
  • Tissue
    sperm
Genes
H2-T3 histocompatibility 2, T region locus 3
H2-T4 histocompatibility 2, T region locus 4
H2-T5 histocompatibility 2, T region locus 5
H2-T6 histocompatibility-2, T region, locus 6
Polymorphisms
J:7080 Winoto A, et al., Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9
Notes: A 3 kb HpaI fragment derived from cosmid 49.1 was subcloned into the HincII site of M13mp8 and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
HindIII H2-T3 a 3.2kb B10.A-H2h1/(1R), B10.D2-H2d, BALB/c, C57BL/6
b 7.7kb B6.Cg-H2b3/FlaCmwJ, B6.Cg-H2b4/FlaCmwJ, C3H, C57BL/6-H2k
c absent A.AL-H2a1, A.TL-H2t1, AKR, AQR, B10.AKM-H2m/SnJ, B10.BDR1-H2g4, B10.Q-H2q/SgJ, C57BL/10
HindIII H2-T4 a 3.2kb B10.A-H2h1/(1R), B10.D2-H2d, BALB/c, C57BL/6
b 7.7kb B6.Cg-H2b3/FlaCmwJ, B6.Cg-H2b4/FlaCmwJ, C3H, C57BL/6-H2k
c absent A.AL-H2a1, A.TL-H2t1, AKR, AQR, B10.AKM-H2m/SnJ, B10.BDR1-H2g4, B10.Q-H2q/SgJ, C57BL/10
References
J:20104 Steinmetz M, et al., Clusters of genes encoding mouse transplantation antigens. Cell. 1982 Mar;28(3):489-98
J:7080 Winoto A, et al., Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex. Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9
J:4087 Hunt SW 3rd, et al., Fine map of a region homologous to the rat grc complex in the TL region of the mouse. Immunogenetics. 1993;37(5):386-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/05/2024
MGI 6.24 		The Jackson Laboratory