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p597.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    p597.1
  • Sequence Type
    genomic
  • ID
    MGI:13249
  • Region Covered
    unique cellular sequence flanking the proviral insertion site
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    500bp
  • Synonyms
    probe B
Source
  • Species
    mouse, laboratory
  • Strain
    BXH2/TyJ
  • Tissue
    myeloid tumor
Genes
Evi2a ecotropic viral integration site 2a
Sequences
M34896 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
M34897 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:9562 Buchberg AM, et al., Oncogene Res. 1988;2(2):149-65
Endonuclease Gene Allele Fragments Strains
BamHI Evi2a a not given AKR/J
b not given A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
EcoRI Evi2a a not given AKR/J
b not given A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
EcoRV Evi2a a not given AKR/J
b not given A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
HindIII Evi2a a 1.9kb AKR/J
b 2.3kb A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
MspI Evi2a a 6.7kb AKR/J
b 6.8kb A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
TaqI Evi2a a 4.4kb AKR/J
b 2.0kb A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
s 1.7kb M. spretus
J:9831 Buchberg AM, et al., Genetics. 1989 May;122(1):153-61
Endonuclease Gene Allele Fragments Strains
TaqI Evi2a b 2.1kb C57BL/6J
s 1.7kb M. spretus
J:1905 Takahashi Y, et al., J Exp Med. 1992 Mar 1;175(3):873-6
Endonuclease Gene Allele Fragments Strains
StuI Evi2a a 4.9kb AKR/Ms, BALB/c
b 5.4kb C57BL/6N
J:20027 Mock BA, et al., Eur J Immunogenet. 1994 Aug;21(4):231-8
Notes: A 500bp SalI/EcoRI fragment of p597.1 was used as a hybridization probe on Southern blots.
Endonuclease Gene Allele Fragments Strains
HindIII Evi2a c 4.3,1.8kb BALB/cAnPt
s 4.3,2.3kb M. spretus
J:22862 Kozak CA, et al., Mamm Genome. 1995 Feb;6(2):142-4
Endonuclease Gene Allele Fragments Strains
BamHI Evi2a n not given C58/J, NFS/N
s not given M. spretus
EcoRI Evi2a m not given M. m. musculus
n not given C58/J, NFS/N
J:24223 Blackburn CC, et al., Genomics. 1995 Mar 20;26(2):308-17
Endonuclease Gene Allele Fragments Strains
StuI Evi2a a 5.4kb A.SW-H2s/Sn, C.Foxn1nu, CBA.NU, CBA/CaH, NZC, NZC.NU, NZW, NZW.NU
c 4.9kb BALB/cAn
References
J:9562 Buchberg AM, et al., Localization of Evi-2 to chromosome 11: linkage to other proto-oncogene and growth factor loci using interspecific backcross mice. Oncogene Res. 1988;2(2):149-65
J:9831 Buchberg AM, et al., A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human. Genetics. 1989 May;122(1):153-61
J:10694 Buchberg AM, et al., Evi-2, a common integration site involved in murine myeloid leukemogenesis. Mol Cell Biol. 1990 Sep;10(9):4658-66
J:1905 Takahashi Y, et al., Mapping of the nu gene using congenic nude strains and in situ hybridization. J Exp Med. 1992 Mar 1;175(3):873-6
J:20027 Mock BA, et al., The inducible form of nitric oxide synthase (NOS2) isolated from murine macrophages maps near the nude mutation on mouse chromosome 11. Eur J Immunogenet. 1994 Aug;21(4):231-8
J:22862 Kozak CA, et al., Localization of three genes expressed in retina on mouse chromosome 11. Mamm Genome. 1995 Feb;6(2):142-4
J:24223 Blackburn CC, et al., A high-resolution map of the chromosomal region surrounding the nude gene. Genomics. 1995 Mar 20;26(2):308-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
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