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Igk-VSer specific probe Probe Detail
Nucleotide
Probe/Clone
  • Name
    Igk-VSer specific probe
  • Sequence Type
    cDNA
  • ID
    MGI:13254
  • Region Covered
    encodes 5' flanking region leader sequence and 5'-portion of V gene segment
  • Parent Clone
    p9(35)
  • Vector Type
    Plasmid
  • Insert Site
    PstI/KpnI
  • Insert Size
    200 bp
Source
  • Species
    mouse, laboratory
  • Strain
    C.C58
  • Tissue
    myeloblast
  • Cell Line
    myeloma cell line M75
Genes
Igkc immunoglobulin kappa constant
Igk-V28 immunoglobulin kappa chain variable 28 (V28)
Sequences
M12177 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
X02816 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7944 Goldrick MM, et al., J Exp Med. 1985 Aug 1;162(2):713-28
Endonuclease Gene Allele Fragments Strains
BamHI Igk-V28 a 3.2kb AKR/J, C57BL/6-Cd8aa, C57BL/6-Cd8bb, C58/J, C.AK, C.C58, NAK, PL/J, RF/J
b 7.8kb A/J, B6.PL-Cd8aa Cd8b1a/(85NS)CyJ, BALB/cAn, BALB/cJ, C3H/HeJ, C57BL/6J, CBA/J, SJL/J, SWR/J
EcoRI Igk-V28 a 2.1kb AKR/J, C57BL/6-Cd8aa, C57BL/6-Cd8bb, C58/J, C.AK, C.C58, PL/J, RF/J
b 2.8kb A/J, B6.PL-Cd8aa Cd8b1a/(85NS)CyJ, BALB/cAn, BALB/cJ, C3H/HeJ, C57BL/6J, CBA/J, SJL/J, SWR/J
HindIII Igk-V28 a 2.8kb AKR/J, C57BL/6-Cd8aa, C57BL/6-Cd8bb, C58/J, C.AK, C.C58, NAK, PL/J, RF/J
b 8.4kb A/J, BALB/cAn, BALB/cJ, C3H/HeJ, C57BL/6J, CBA/J, SJL/J, SWR/J
References
J:7944 Goldrick MM, et al., Molecular genetic analysis of the V kappa Ser group associated with two mouse light chain genetic markers. Complementary DNA cloning and southern hybridization analysis. J Exp Med. 1985 Aug 1;162(2):713-28
J:9700 Ponath PD, et al., Structural and evolutionary comparisons of four alleles of the mouse immunoglobulin kappa chain gene, Igk-VSer. Immunogenetics. 1989;29(4):249-57
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory