C5.23 Probe Detail MGI Mouse MGI:13263

C5.23 Probe Detail

Name

C5.23
Sequence Type

genomic
ID

MGI:13263
Region Covered

encodes a portion of the intron between exons 6 and 7 encodes a portion of the intron between 6 and 7
Parent Clone

cosmid C5
Vector Type

Plasmid
Insert Site

SstI
Insert Size

120 bp

Species

mouse, laboratory

H2-Q5	histocompatibility 2, Q region locus 5
H2-Q7	histocompatibility 2, Q region locus 7
H2-Q9	histocompatibility 2, Q region locus 9

J:8531 O'Neill AE, et al., Immunogenetics. 1986;24(6):368-73

Notes: Because the H-2Q5, H-2Q7 and H-2Q9 genes share many restriction sites, Southern analyses utilizing this probe and most restriction enzymes are unable to distinguish between these three loci.

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	H2-Q5	a	5kb	B6.Cg-H2^b3/FlaCmwJ
		b	2.7kb	B6.Cg-H2^b4/FlaCmwJ
		c	absent	B10.M-H2^f/Sn
BamHI	H2-Q7	a	5.0kb	B6.Cg-H2^b3/FlaCmwJ
		b	2.7kb	B6.Cg-H2^b4/FlaCmwJ
		c	absent	B10.M-H2^f/Sn
BamHI	H2-Q9	a	5.0kb	B6.Cg-H2^b3/FlaCmwJ
		b	2.7kb	B6.Cg-H2^b4/FlaCmwJ
		c	absent	B10.M-H2^f/Sn

J:8531 O'Neill AE, et al., Extensive deletions in the Q region of the mouse major histocompatibility complex. Immunogenetics. 1986;24(6):368-73

J:557 Uehara H, et al., Molecular organization of the D-Qa region of t-haplotypes suggests that recombination is an important mechanism for generating genetic diversity of the major histocompatibility complex. Mamm Genome. 1991;1(2):92-9

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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